Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …

The monoamine serotonin, 5-hydroxytryptamine (5-HT), is a remarkable molecule with
conserved production in prokaryotes and eukaryotes and a wide range of functions. In the …

Leukocyte trafficking to the gastrointestinal tract is recognized to play a role in the
pathogenesis of inflammatory bowel disease (IBD). Integrins are expressed on immune cells …

Nowadays, non-biological treatments remain valuable approaches among the therapeutic
armamentarium of inflammatory bowel disease (IBD). Mesalamine is the core treatment of …

Inflammation often develops from acute, chronic, or auto-inflammatory disorders that can
lead to compromised organ function. Cannabis (Cannabis sativa) has been used to treat …

Background Recent evidence is supporting the notion of a microbiological and
immunological continuum on the gum–gut axis in health and disease. Therefore, the …

Butyrate is a short-chain fatty acid that plays a key role in maintaining gut homeostasis as
well as the integrity of the intestinal barrier. In the present study, we investigated the effect of …

Aim Our aim was to compare the risk of developing inflammatory bowel disease [IBD]
between ever users and never users of metformin. Methods Patients with newly diagnosed …

ABSTRACT Inflammatory Bowel Disease (IBD) is a chronic immune-mediated inflammatory
disease of the gastrointestinal tract that is a growing public burden. Gut microbes and their …

Background The inflammatory bowel diseases, Crohn's disease and ulcerative colitis are
related multifactorial diseases. Their pathogenesis is influenced by each individual's …