Dysregulation of brain reward systems in eating disorders: neurochemical information from animal models of binge eating, bulimia nervosa, and anorexia nervosa

NM Avena, ME Bocarsly - Neuropharmacology, 2012 - Elsevier
Food intake is mediated, in part, through brain pathways for motivation and reinforcement.
Dysregulation of these pathways may underlay some of the behaviors exhibited by patients …

Appetite and reward

S Fulton - Frontiers in neuroendocrinology, 2010 - Elsevier
The tendency to engage in or maintain feeding behaviour is potently influenced by the
rewarding properties of food. Affective and goal-directed behavioural responses for food …

Role of ghrelin in food reward: impact of ghrelin on sucrose self‐administration and mesolimbic dopamine and acetylcholine receptor gene expression

KP Skibicka, C Hansson, E Egecioglu… - Addiction …, 2012 - Wiley Online Library
The decision to eat is strongly influenced by non‐homeostatic factors such as food
palatability. Indeed, the rewarding and motivational value of food can override homeostatic …

The role of histaminergic H1 and H3 receptors in food intake: a mechanism for atypical antipsychotic-induced weight gain?

C Deng, K Weston-Green, XF Huang - Progress in Neuro …, 2010 - Elsevier
Atypical antipsychotics such as olanzapine and clozapine are effective at treating the
multiple domains of schizophrenia, with a low risk of extra-pyramidal side-effects. However a …

Effects of acute administration of nicotinic and muscarinic cholinergic agonists and antagonists on performance in different cost–benefit decision making tasks in rats

IA Mendez, RJ Gilbert, JL Bizon, B Setlow - Psychopharmacology, 2012 - Springer
Rationale Alterations in cost–benefit decision making accompany numerous
neuropsychiatric conditions, including schizophrenia, attention deficit hyperactivity disorder …

Central injection of relaxin-3 receptor (RXFP3) antagonist peptides reduces motivated food seeking and consumption in C57BL/6J mice

CM Smith, BE Chua, C Zhang, AW Walker… - Behavioural brain …, 2014 - Elsevier
Behavioural arousal in mammals is regulated by various interacting central monoamine-and
peptide-neurotransmitter/receptor systems, which function to maintain awake, alert and …

Principles of motivation revealed by the diverse functions of neuropharmacological and neuroanatomical substrates underlying feeding behavior

BA Baldo, WE Pratt, MJ Will, EC Hanlon… - Neuroscience & …, 2013 - Elsevier
Circuits that participate in specific subcomponents of feeding (eg, gustatory perception,
peripheral feedback relevant to satiety and energy balance, reward coding, etc.) are found at …

Modulatory role of serotonin on feeding behavior

CP Magalhães, MFL de Freitas, MI Nogueira… - Nutritional …, 2010 - Taylor & Francis
The appearance, the odor, and the flavor of foods, all send messages to the encephalic area
of the brain. The hypothalamus, in particular, plays a key role in the mechanisms that control …

Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens

P Rada, JR Barson, SF Leibowitz, BG Hoebel - Brain research, 2010 - Elsevier
The experimental question is whether hypothalamic opioids, known to stimulate
consummatory behavior, control a link to the nucleus accumbens (NAc). It was hypothesized …

Serotonin 1A, 1B, and 7 receptors of the rat medial nucleus accumbens differentially regulate feeding, water intake, and locomotor activity

KA Clissold, E Choi, WE Pratt - Pharmacology Biochemistry and Behavior, 2013 - Elsevier
Abstract Serotonin (5-HT) signaling has been widely implicated in the regulation of feeding
behaviors in both humans and animal models. Recently, we reported that co-stimulation of 5 …