Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …

Spermatogenesis is a concerted sequence of events during maturation of spermatogonia
into spermatozoa. The process involves differential gene-expression and cell-cell interplay …

In vitro generation of functional gametes is a promising approach for treating infertility,
although faithful replication of meiosis has proven to be a substantial obstacle to deriving …

Spermatogenesis and folliculogenesis involve cell–cell interactions and gene expression
orchestrated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH). FSH …

Evaluation of testicular functions (production of sperm and androgens) is an important
aspect of preclinical safety assessment and testicular toxicity is comparatively far more …

Reproductive physiology involves complex biological processes that can be disrupted by
exposure to environmental contaminants. The effects of bisphenol A (BPA) on …

The purpose of this review is to describe the endocrine and local testicular factors that
contribute to the regulation of the blood-testis barrier (BTB), using information gained from in …

Engineered male and female biomimetic reproductive tissues are being developed as
autonomous in vitro units or as integrated multi-organ in vitro systems to support germ cell …

Testosterone is essential for spermatogenesis and male fertility. In this review, topics related
to testosterone control of spermatogenesis are covered including testosterone production …

In the last decade, vitamin D has emerged as a pleiotropic molecule with a multitude of
autocrine, paracrine and endocrine functions, mediated by classical genomic as well as non …