Monoclonal antibody and protein therapeutic formulations for subcutaneous delivery: high-concentration, low-volume vs. low-concentration, high-volume
M Desai, A Kundu, M Hageman, H Lou, D Boisvert - MAbs, 2023 - Taylor & Francis
Biologic drugs are used to treat a variety of cancers and chronic diseases. While most of
these treatments are administered intravenously by trained healthcare professionals, a …
these treatments are administered intravenously by trained healthcare professionals, a …
Intradermal delivery of naked mRNA vaccines via iontophoresis
M Hasan, A Khatun, K Kogure - Pharmaceutics, 2023 - mdpi.com
Messenger RNA (mRNA) vaccines against infectious diseases and for anticancer
immunotherapy have garnered considerable attention. Currently, mRNA vaccines …
immunotherapy have garnered considerable attention. Currently, mRNA vaccines …
[HTML][HTML] Hollow silicon microneedles, fabricated using combined wet and dry etching techniques, for transdermal delivery and diagnostics
Microneedle-based technologies are the subject of intense research and commercial
interest for applications in transdermal delivery and diagnostics, primarily because of their …
interest for applications in transdermal delivery and diagnostics, primarily because of their …
[HTML][HTML] Best practice recommendations for the management of anxiety during the pegvaliase journey
KJ Bjoraker, C Eggerding, E Ellenberg… - Molecular genetics and …, 2024 - Elsevier
Background Pegvaliase, an enzyme substitution therapy, is a treatment option for
phenylketonuria (PKU). Due to the neuropathophysiology and disease burden of PKU …
phenylketonuria (PKU). Due to the neuropathophysiology and disease burden of PKU …
A novel scenario in the therapeutic management of anemia of chronic kidney disease: placement and use of roxadustat
F Locatelli, M Ravera, C Esposito, G Grandaliano… - Journal of …, 2024 - Springer
Anemia is a frequent and early chronic kidney disease (CKD) complication. Its management
is currently based on oral or intravenous iron supplements, erythropoiesis-stimulating …
is currently based on oral or intravenous iron supplements, erythropoiesis-stimulating …
Needle phobia among adult jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
S Abdelghany, S Al-Muhaissen, YA Thaher, M Melhem… - Plos one, 2023 - journals.plos.org
Needle phobia remains a major drawback of conventional injectable medications, leading to
avoidance and low adherence among a reasonable portion of patients. Despite this, there is …
avoidance and low adherence among a reasonable portion of patients. Despite this, there is …
MEDIC: Development and validation of a new instrument to assess emotional reactivity to medical stimuli in a representative community sample of adults
To support investigation of the etiology and psychophysiology of medical traumatic stress,
we developed a standardized set of emotionally-salient medical images, called the 'MEDical …
we developed a standardized set of emotionally-salient medical images, called the 'MEDical …
A Bioinspired and Cost‐Effective Device for Minimally Invasive Blood Sampling
N Zoratto, D Klein‐Cerrejon, D Gao… - Advanced …, 2024 - Wiley Online Library
Conventional venipuncture is invasive and challenging in low and middle‐income countries.
Conversely, point‐of‐care devices paired with fingersticks, although less invasive, suffer …
Conversely, point‐of‐care devices paired with fingersticks, although less invasive, suffer …
Prevalence, factors associated and management of needle phobia among the general population in Saudi Arabia and Egypt
Objective This study aims to assess the prevalence of needle phobia among Saudi and
Egyptian adult populations. In addition, underlying causes and strategies that can be utilized …
Egyptian adult populations. In addition, underlying causes and strategies that can be utilized …
Evaluating unmet needs in large-volume subcutaneous drug delivery: US payer perspectives on a novel, large-volume on-body delivery system
M Desai, J Kenney, E Pezalla - Current Medical Research and …, 2024 - Taylor & Francis
Objective Existing healthcare systems face finite resource allocation and budgetary
constraints, resulting in a substantial need for innovative solutions to enhance service …
constraints, resulting in a substantial need for innovative solutions to enhance service …