[HTML][HTML] A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

[HTML][HTML] Microglia phenotypes in aging and neurodegenerative diseases

MY Wendimu, SB Hooks - Cells, 2022 - mdpi.com
Neuroinflammation is a hallmark of many neurodegenerative diseases (NDs) and plays a
fundamental role in mediating the onset and progression of disease. Microglia, which …

Diagnosis and treatment of Parkinson disease: a review

MJ Armstrong, MS Okun - Jama, 2020 - jamanetwork.com
Importance Parkinson disease is the most common form of parkinsonism, a group of
neurological disorders with Parkinson disease–like movement problems such as rigidity …

[HTML][HTML] The gut–brain axis and its relation to Parkinson's disease: a review

EM Klann, U Dissanayake, A Gurrala… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease is a chronic neurodegenerative disease characterized by the
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …

[HTML][HTML] MPTP-induced mouse model of Parkinson's disease: A promising direction for therapeutic strategies

M Mustapha, CNM Taib - Bosnian journal of basic medical …, 2021 - ncbi.nlm.nih.gov
Among the popular animal models of Parkinson's disease (PD) commonly used in research
are those that employ neurotoxins, especially 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

[HTML][HTML] Glucagon-like peptide-1: A multi-faceted anti-inflammatory agent

SF Mehdi, S Pusapati, MS Anwar, D Lohana… - Frontiers in …, 2023 - frontiersin.org
Inflammation contributes to many chronic conditions. It is often associated with circulating
pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity …

[HTML][HTML] Alpha-synuclein aggregation pathway in Parkinson's disease: current status and novel therapeutic approaches

M Vidović, MG Rikalovic - Cells, 2022 - mdpi.com
Following Alzheimer's, Parkinson's disease (PD) is the second-most common
neurodegenerative disorder, sharing an unclear pathophysiology, a multifactorial profile …

[HTML][HTML] Sodium benzoate—Harmfulness and potential use in therapies for disorders related to the nervous system: A review

ŁJ Walczak-Nowicka, M Herbet - Nutrients, 2022 - mdpi.com
Currently, due to the large number of reports regarding the harmfulness of food additives,
more and more consumers follow the so-called “clean label” trend, ie, prefer and choose the …

[HTML][HTML] Alpha-synuclein as a biomarker of Parkinson's disease: good, but not good enough

U Ganguly, S Singh, S Pal, S Prasad… - Frontiers in aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disorder of the
elderly, presenting primarily with symptoms of motor impairment. The disease is diagnosed …

[HTML][HTML] DHA/EPA (Omega-3) and LA/GLA (Omega-6) as bioactive molecules in neurodegenerative diseases

C Kousparou, M Fyrilla, A Stephanou… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases are characterized by neuroinflammation, neuronal depletion
and oxidative stress. They coincide with subtle chronic or flaring inflammation, sometimes …