Nucleoid associated proteins: the small organizers that help to cope with stress
J Hołówka, J Zakrzewska-Czerwińska - Frontiers in microbiology, 2020 - frontiersin.org
The bacterial chromosome must be efficiently compacted to fit inside the small and crowded
cell while remaining accessible for the protein complexes involved in replication …
cell while remaining accessible for the protein complexes involved in replication …
Xenogeneic silencing and bacterial genome evolution: mechanisms for DNA recognition imply multifaceted roles of xenogeneic silencers
Horizontal gene transfer (HGT) is a major driving force for bacterial evolution. To avoid the
deleterious effects due to the unregulated expression of newly acquired foreign genes …
deleterious effects due to the unregulated expression of newly acquired foreign genes …
Pangenome-level analysis of nucleoid-associated proteins in the Acidithiobacillia class: insights into their functional roles in mobile genetic elements biology
S Beard, A Moya-Beltrán, D Silva-García… - Frontiers in …, 2023 - frontiersin.org
Mobile genetic elements (MGEs) are relevant agents in bacterial adaptation and
evolutionary diversification. Stable appropriation of these DNA elements depends on host …
evolutionary diversification. Stable appropriation of these DNA elements depends on host …
Mutation bias and adaptation in bacteria
Genetic mutation, which provides the raw material for evolutionary adaptation, is largely a
stochastic force. However, there is ample evidence showing that mutations can also exhibit …
stochastic force. However, there is ample evidence showing that mutations can also exhibit …
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence
within patients and how these vary across bacterial infections are poorly understood …
within patients and how these vary across bacterial infections are poorly understood …
Ensifer meliloti L6-AK89, an Effective Inoculant of Medicago lupulina Varieties: Phenotypic and Deep-Genome Screening
ML Roumiantseva, ME Vladimirova, AS Saksaganskaia… - Agronomy, 2022 - mdpi.com
This paper presents a deep analysis of the accessory genome of an economically promising
strain of Ensifer (Sinorhizobium) meliloti, L6-AK89, obtained as a result of next-generation …
strain of Ensifer (Sinorhizobium) meliloti, L6-AK89, obtained as a result of next-generation …
Modeling the mosaic structure of bacterial genomes to infer their evolutionary history
M Sheinman, PF Arndt… - Proceedings of the …, 2024 - National Acad Sciences
The chronology and phylogeny of bacterial evolution are difficult to reconstruct due to a
scarce fossil record. The analysis of bacterial genomes remains challenging because of …
scarce fossil record. The analysis of bacterial genomes remains challenging because of …
Natural Chromosome-Chromid Fusion across rRNA Operons in a Burkholderiaceae Bacterium
JF Mori, RA Kanaly - Microbiology spectrum, 2022 - Am Soc Microbiol
Chromids (secondary chromosomes) in bacterial genomes that are present in addition to the
main chromosome appear to be evolutionarily conserved in some specific bacterial groups …
main chromosome appear to be evolutionarily conserved in some specific bacterial groups …
Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS
O Dagva, A Thibessard, JN Lorenzi… - Nucleic Acids …, 2024 - academic.oup.com
The linear chromosome of Streptomyces exhibits a highly compartmentalized structure with
a conserved central region flanked by variable arms. As double strand break (DSB) repair …
a conserved central region flanked by variable arms. As double strand break (DSB) repair …
Spatiotemporal Manipulation of the Mismatch Repair System of Pseudomonas putida Accelerates Phenotype Emergence
L Fernández-Cabezón, A Cros, PI Nikel - ACS Synthetic Biology, 2021 - ACS Publications
The development of complex phenotypes in industrially relevant bacteria is a major goal of
metabolic engineering, which encompasses the implementation of both rational and random …
metabolic engineering, which encompasses the implementation of both rational and random …