Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole-and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer's Disease
Alzheimer's disease (AD) is considered a complex neurodegenerative condition which
warrants the development of multitargeted drugs to tackle the key pathogenetic mechanisms …
warrants the development of multitargeted drugs to tackle the key pathogenetic mechanisms …
Exogenous melatonin protects against oxidative damage to membrane lipids caused by some sodium/iodide symporter inhibitors in the thyroid
AK Gładysz, J Stępniak, M Karbownik-Lewińska - Antioxidants, 2023 - mdpi.com
The thyroid gland is the primary site of sodium/iodide symporter (NIS), an intrinsic plasma
membrane protein responsible for the active uptake of iodine, which is indispensable for …
membrane protein responsible for the active uptake of iodine, which is indispensable for …
Two 5-Methoxyindole Carboxylic Acid-Derived Hydrazones of Neuropharmacological Interest: Synthesis, Crystal Structure, and Chemiluminescent Study of Radical …
N Anastassova, N Hristova-Avakumova, R Rusew… - Crystals, 2024 - mdpi.com
Given the importance of molecular structure in pharmacological activity and interaction with
biological receptors, we conducted a study on the 3, 4-dihydroxybenzaldehyde hydrazone …
biological receptors, we conducted a study on the 3, 4-dihydroxybenzaldehyde hydrazone …