Mechanisms and prevention of UV‐induced melanoma

A Sample, YY He - Photodermatology, photoimmunology & …, 2018 - Wiley Online Library
Melanoma is the deadliest form of skin cancer and its incidence is rising, creating a costly
and significant clinical problem. Exposure to ultraviolet (UV) radiation, namely UVA (315 …

Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics

AM Juszczak, U Wöelfle, MZ Končić… - Medicinal research …, 2022 - Wiley Online Library
Cutaneous malignant melanoma is the fastest growing and the most aggressive form of skin
cancer that is diagnosed. However, its incidence is relatively scarce compared to the highest …

Phenolic compounds of blueberries (Vaccinium spp) as a protective strategy against skin cell damage induced by ROS: A review of antioxidant potential and …

DA Maya-Cano, S Arango-Varela, GA Santa-Gonzalez - Heliyon, 2021 - cell.com
The skin is a tissue with a high metabolic activity that acts as a protective layer for the
internal organs of the body. This tissue is exposed to a variety of damaging agents, including …

[HTML][HTML] Trigonelline, a plant derived alkaloid prevents ultraviolet-B-induced oxidative DNA damage in primary human dermal fibroblasts and BALB/c mice via …

MA Tanveer, H Rashid, LA Nazir, S Archoo… - Experimental …, 2023 - Elsevier
Background DNA is the main target for UV-B-irradiation-induced skin photodamage and
accounts for 90% of all the non-melanoma skin cancers. Purpose In this study, we explored …

Characterization of Cistus × incanus L. and Cistus ladanifer L. Extracts as Potential Multifunctional Antioxidant Ingredients for Skin Protecting Cosmetics

K Gaweł-Bęben, W Kukula-Koch, U Hoian, M Czop… - Antioxidants, 2020 - mdpi.com
Skin is constantly exposed to harmful environmental factors, causing photo-oxidative stress
in cells and leading to the development of health and aesthetic problems. Multifunctional …

Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models

T Li, X Fu, B Liu, X Wang, J Li, P Zhu, X Niu… - Biochemical …, 2022 - Elsevier
Signal transducer and activator of transcription 3 (STAT3) has been proposed as a target for
melanoma prevention. Luteolin, a bioactive flavonoid abundant in medicinal herbs, has …

Prostate cancer chemoprevention by natural agents: Clinical evidence and potential implications

G Chhabra, CK Singh, MA Ndiaye, S Fedorowicz… - Cancer letters, 2018 - Elsevier
Prostate cancer (PCa) is the most common non-skin cancer and the second leading cause
of cancer-related deaths in American men. Due to its long latency period, PCa is considered …

NRF2 and key transcriptional targets in melanoma redox manipulation

EL Carpenter, AL Becker, AK Indra - Cancers, 2022 - mdpi.com
Simple Summary Melanocytes are the pigment-producing cells in the skin that help to
protect it against damaging solar ultraviolet radiation. As they engage in this function, they …

Chemoprevention agents for melanoma: a path forward into phase 3 clinical trials

JM Jeter, TL Bowles, C Curiel‐Lewandrowski… - Cancer, 2019 - Wiley Online Library
Recent progress in the treatment of advanced melanoma has led to unprecedented
improvements in overall survival and, as these new melanoma treatments have been …

Etiologies of melanoma development and prevention measures: A review of the current evidence

AR Djavid, C Stonesifer, BT Fullerton, SW Wang… - Cancers, 2021 - mdpi.com
Simple Summary Melanoma constitutes a major public health risk, with the rates of
diagnosis increasing on a yearly basis. Monitoring for risk factors and preventing dangerous …