MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

The considerable mortality and morbidity associated with atrial fibrillation (AF) pose a
substantial burden on patients and health care services. Although the management of AF …

Background Atrial fibrillation is the most frequent sustained arrhythmia. Atrial fibrillation often
recurs after restoration of normal sinus rhythm. Antiarrhythmic drugs have been widely used …

Objective To assess the efficacy and safety of catheter ablation (CA) compared with
antiarrhythmic drugs (AADs) as first-line treatment for symptomatic paroxysmal atrial …

Historically, atrial fibrillation has been observed in clinical settings of prolonged
hemodynamic stress, eg, hypertension and valvular heart disease. However, recently, the …

Background Current guidelines recommend rhythm control for improving symptoms and
quality of life in symptomatic patients with atrial fibrillation (AF). However, the long-term …

Background Use of rate/rhythm control is essential to control symptoms in patients with atrial
fibrillation (AF). Recently, the EAST-AFNET 4 trial described how early rhythm control …

Heart failure with preserved ejection fraction (HFpEF) is associated with multiple
cardiovascular and noncardiovascular comorbidities and risk factors which increase the risk …

Genome-wide association studies found that increased risk for atrial fibrillation (AF), the
most common human heart arrhythmia, is associated with noncoding sequence variants …

Atrial fibrillation (AF) is the most frequent chronic arrhythmia worldwide, and it is associated
with significant morbidity and mortality, making it a considerable burden both to patients and …