Applications of fluorescence in situ hybridization (FISH) in detecting genetic aberrations of medical significance

R Bishop - Bioscience Horizons, 2010 - academic.oup.com
Fluorescence in situ hybridization (FISH) is a powerful technique used in the detection of
chromosomal abnormalities. The high sensitivity and specificity of FISH and the speed with …

[HTML][HTML] Mouse models for lung cancer

M Kwon, A Berns - Molecular oncology, 2013 - Elsevier
Lung cancer is a devastating disease and a major therapeutic burden with poor survival
rates. It is responsible for 30% of all cancer deaths. Lung cancer is strongly associated with …

Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and …

H Kantarjian, C Schiffer, D Jones… - Blood, The Journal of …, 2008 - ashpublications.org
The management of hematologic malignancies, including chronic myeloid leukemia (CML),
chronic lymphocytic leukemia (CLL), and acute lymphocytic leukemia (ALL), has led the way …

Transcriptional spatial profiling of cancer tissues in the era of immunotherapy: the potential and promise

SN Nerurkar, D Goh, CCL Cheung, PQY Nga, JCT Lim… - Cancers, 2020 - mdpi.com
Simple Summary In recent years, immunotherapy has emerged as a pillar in the fight against
cancer. However, the heterogeneity within the tumor microenvironment poses challenges to …

Dual-modal label-free genosensor based on hemoglobin@ gold nanocluster stabilized graphene nanosheets for the electrochemical detection of BCR/ABL fusion …

M Shamsipur, L Samandari, L Farzin, F Molaabasi… - Talanta, 2020 - Elsevier
For the first time, we have successfully synthesized stable graphene nanosheets from
graphite powder through sonication in the hemoglobin-capped gold nanoclusters (Hb …

[图书][B] Atlas of differential diagnosis in neoplastic hematopathology

W Gorczyca - 2021 - taylorfrancis.com
This atlas presents not only the differential diagnosis but also the detailed morphologic,
immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid …

Statistical treatment of fluorescence in situ hybridization validation data to generate normal reference ranges using Excel functions

AL Ciolino, ME Tang, R Bryant - The Journal of Molecular Diagnostics, 2009 - Elsevier
Fluorescent in situ hybridization has become an essential tool for diagnosing and monitoring
hematological disease. Testing for minimal residual disease requires precise and accurate …

Comparison of FISH and Quantitative RT-PCR for the Diagnosis and Follow-Up of BCR-ABL-Positive Leukemias

F Bao, R Munker, C Lowery, S Martin, R Shi… - Molecular diagnosis & …, 2007 - Springer
Abstract Background: For Philadelphia chromosome positive (Ph+) leukemias (chronic
myelogenous leukemia [CML], acute lymphoblastic leukemia [ALL], and rare other …

Application and interpretation of FISH in biomarker studies

J Bayani, JA Squire - Cancer letters, 2007 - Elsevier
Emerging genomic and proteomic data is creating new opportunities to identify novel
biomarkers that will have pathway-specific therapeutic impact on cancer progression …

Gene expression profiling of chronic myeloid leukemia with variant t (9; 22) reveals a different signature from cases with classic translocation

F Albano, A Zagaria, L Anelli, N Coccaro, L Impera… - Molecular cancer, 2013 - Springer
Abstract Background The t (9; 22)(q34; q11) generating the BCR/ABL1 fusion gene
represents the cytogenetic hallmark of chronic myeloid leukemia (CML). About 5–10% of …