Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …

There is a growing awareness of the importance of sex and gender in medicine and
research. Women typically have stronger immune responses to self and foreign antigens …

Abstract Background Efforts to prevent Clostridioides difficile infection continue to expand
across the health care spectrum in the United States. Whether these efforts are reducing the …

Importance A safe and effective treatment for recurrentClostridioides difficileinfection (CDI) is
urgently needed. Antibiotics kill toxin-producing bacteria but do not repair the disrupted …

Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Background The magnitude and scope of Clostridium difficile infection in the United States
continue to evolve. Methods In 2011, we performed active population-and laboratory-based …

This article reviews the pathogenesis, epidemiology, diagnosis, and treatment of this
nosocomial and potentially fatal infectious diarrhea, as well as the associated risk factors …

Clostridium difficile is a major cause of intestinal infection and diarrhoea in individuals
following antibiotic treatment. Recent studies have begun to elucidate the mechanisms that …

Background Clostridium difficile is a leading cause of morbidity and mortality in several
countries. However, there are limited evidence characterizing its role as a global public …

AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …