Differences in muscle satellite cell dynamics during muscle hypertrophy and regeneration

S Fukada, T Higashimoto, A Kaneshige - Skeletal muscle, 2022 - Springer
Skeletal muscle homeostasis and function are ensured by orchestrated cellular interactions
among several types of cells. A noticeable aspect of skeletal muscle biology is the drastic …

[PDF][PDF] Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

A Kaneshige, T Kaji, L Zhang, H Saito, A Nakamura… - Cell Stem Cell, 2022 - cell.com
Adaptation to mechanical load, leading to enhanced force and power output, is a
characteristic feature of skeletal muscle. Formation of new myonuclei required for efficient …

The role and therapeutic potential of stem cells in skeletal muscle in sarcopenia

Z Cai, D Liu, Y Yang, W Xie, M He, D Yu, Y Wu… - Stem Cell Research & …, 2022 - Springer
Sarcopenia is a common age-related skeletal muscle disorder featuring the loss of muscle
mass and function. In regard to tissue repair in the human body, scientists always consider …

[HTML][HTML] Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

H Xiao, LHM Bozi, Y Sun, CL Riley, VM Philip, M Chen… - Cell, 2022 - cell.com
Brown adipose tissue (BAT) regulates metabolic physiology. However, nearly all
mechanistic studies of BAT protein function occur in a single inbred mouse strain, which has …

Bioinspired supramolecular hydrogel from design to applications

F Gao, X Yang, W Song - Small Methods, 2024 - Wiley Online Library
Nature offers a wealth of opportunities to solve scientific and technological issues based on
its unique structures and function. The dynamic non‐covalent interaction is considered to be …

Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function

I Lei, W Huang, PE Noly, S Naik, M Ghali… - Science translational …, 2023 - science.org
Preservation quality of donor hearts is a key determinant of transplant success. Preservation
duration beyond 4 hours is associated with primary graft dysfunction (PGD). Given transport …

Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasion

R Yan, P Zhang, S Shen, Y Zeng, T Wang, Z Chen… - Nature …, 2024 - nature.com
Tumor cells and surrounding immune cells undergo metabolic reprogramming, leading to an
acidic tumor microenvironment. However, it is unclear how tumor cells adapt to this acidic …

Oxidative stress and metabolism meet epigenetic modulation in physical exercise

JL García-Giménez, I Cánovas-Cervera… - Free Radical Biology and …, 2024 - Elsevier
Physical exercise is established as an important factor of health and generally is
recommended for its positive effects on several tissues, organs, and systems. These positive …

Intertwined relationship of mitochondrial metabolism, gut microbiome and exercise potential

S Imdad, W Lim, JH Kim, C Kang - International Journal of Molecular …, 2022 - mdpi.com
The microbiome has emerged as a key player contributing significantly to the human
physiology over the past decades. The potential microbial niche is largely unexplored in the …

An evolving view of complex II—noncanonical complexes, megacomplexes, respiration, signaling, and beyond

TM Iverson, PK Singh, G Cecchini - Journal of Biological Chemistry, 2023 - ASBMB
Mitochondrial complex II is traditionally studied for its participation in two key respiratory
processes: the electron transport chain and the Krebs cycle. There is now a rich body of …