Autoimmunity may be a manifestation of inborn errors of immunity, specifically as part of the
subgroup of primary immunodeficiency known as primary immune regulatory disorders …

Anticytokine autoantibodies can cause immunodeficiency or dysregulate immune
responses. They may phenocopy genetically defined primary immunodeficiencies. We …

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19
pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-α2 in 10 patients …

Background: The recent COVID-19 pandemic produced a significant increase in cases and
an emergency state was induced worldwide. The current knowledge about the COVID-19 …

Devastating pandemics, such as that due to COVID-19, can provide strong testimony to our
knowledge of the genetic and evolutionary determinants of infectious disease susceptibility …

Long COVID-19 is a recognized entity that affects millions of people worldwide. Its broad
clinical symptoms include thrombotic events, brain fog, myocarditis, shortness of breath …

Abstract Coronavirus disease 2019 (COVID-19) has had profound effects on the health of
individuals and on healthcare systems worldwide. While healthcare workers on the …

The latest WHO report determined the increasing diversity within the CoV-2 omicron and its
descendent lineages. Some heavily mutated offshoots of BA. 5 and BA. 2, such as BA. 4.6 …

Purpose Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies
against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for …

A continual increase in cases of Long/Post COVID constitutes a medical and socioeconomic
challenge to health systems around the globe. While the true extent of this problem cannot …