Background The clinical outcome of COVID-19 pneumonia is highly variable. Few biological
predictive factors have been identified. Genetic and immunological studies suggest that type …

Fungi are opportunists: They particularly require a defect of immunity to cause severe or
disseminated disease. While often secondary to an apparent iatrogenic cause, fungal …

During the last two years, treatment of patients with novel coronavirus infection COVID-19
remains an urgent health problem. Interferon proteins are known to play a significant role in …

Objective We sought to explore the prevalence of type I interferon-neutralizing antibodies in
a Chinese cohort and its clinical implications during the Omicron variant wave of SARS-CoV …

Host-directed immunotherapy to fight infectious diseases : Current Opinion in Pediatrics
Host-directed immunotherapy to fight infectious diseases : Current Opinion in Pediatrics Log in …

The novel coronavirus-19 (SARS-CoV-2), has infected numerous individuals worldwide,
resulting in millions of fatalities. The pandemic spread with high mortality rates in multiple …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces pneumonia and
acute respiratory failure in Coronavirus Disease 2019 (COVID-19) patients with inborn …

Several genetic and immunological risk factors for severe COVID-19 have been identified,
with monogenic conditions relating to 13 genes of type I interferon (IFN) immunity proposed …

Purpose Auto-antibodies (auto-abs) to type I interferons (IFNs) have been identified in
patients with life-threatening coronavirus disease 2019 (COVID-19), suggesting that the …

Definition Infection with SARS-CoV-2 and the resulting COVID-19 can cause both lung and
kidney damage. SARS-CoV-2 can directly infect renal cells expressing ACE2 receptors …