Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Mito‐bomb: targeting mitochondria for cancer therapy

X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …

Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications

J Zielonka, J Joseph, A Sikora, M Hardy… - Chemical …, 2017 - ACS Publications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

Z Zhou, J Song, L Nie, X Chen - Chemical society reviews, 2016 - pubs.rsc.org
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

Recent advances in nanomaterials for enhanced photothermal therapy of tumors

JJ Hu, YJ Cheng, XZ Zhang - Nanoscale, 2018 - pubs.rsc.org
Nowadays, photothermal therapy (PTT) utilizing photothermal conversion agents (PTAs) to
generate sufficient heat under near-infrared (NIR) light irradiation for tumor ablation has …

Recent advances of multi-dimensional porphyrin-based functional materials in photodynamic therapy

J Tian, B Huang, MH Nawaz, W Zhang - Coordination Chemistry Reviews, 2020 - Elsevier
Photodynamic therapy (PDT) has emerged as a promising and non-invasive modality for
cancer treatments. Photosensitizers, as one of the essential elements in PDT, play a crucial …

Self‐assembled peptide‐based nanomaterials for biomedical imaging and therapy

GB Qi, YJ Gao, L Wang, H Wang - Advanced materials, 2018 - Wiley Online Library
Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …