All mammalian species depend on the placenta, a transient organ, for exchange of gases,
nutrients, and waste between the mother and conceptus. Besides serving as a conduit for …

Appropriate in utero growth is essential for offspring development and is a critical contributor
to long-term health. Fetal growth is largely dictated by the availability of nutrients in maternal …

The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

The recent and rapid worldwide increase in non-communicable diseases challenges the
assumption that genetic factors are the primary contributors to such diseases. A new concept …

Aim The current study investigated the impact of maternal obesity on placental phenotype in
relation to fetal growth and sex. Methods Female C57BL6/J mice were fed either a diet high …

The contributions of maternal diet and obesity in shaping offspring microbiome remain
unclear. Here we employed a mouse model of maternal diet-induced obesity via high-fat diet …

Epigenetic mechanisms, often defined as regulating gene activity independently of
underlying DNA sequence, are crucial for healthy development. The sum total of epigenetic …

Background Airborne pollution is a rising concern in urban areas. Epidemiological studies in
humans and animal experiments using rodent models indicate that gestational exposure to …

The placenta is vital for mammalian development and a key determinant of life‐long health.
It is the interface between the mother and fetus and is responsible for transporting the …

During formation of the preimplantation embryo several cellular and molecular milestones
take place, making the few cells forming the early embryo vulnerable to environmental …