[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins

BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

Retinal pigment epithelium-secretome: A diabetic retinopathy perspective

M Ponnalagu, M Subramani, C Jayadev, R Shetty… - Cytokine, 2017 - Elsevier
Diabetic retinopathy is a major complication of diabetes mellitus that can lead to retinal
vascular abnormalities and visual impairment. While retinal endothelial pathology is well …

[HTML][HTML] Chitosan-coated PLGA nanoparticles encapsulating triamcinolone acetonide as a potential candidate for sustained ocular drug delivery

M Dandamudi, P McLoughlin, G Behl, S Rani, L Coffey… - Pharmaceutics, 2021 - mdpi.com
The current treatment for the acquired retinal vasculopathies involves lifelong repeated
intravitreal injections of either anti-vascular endothelial growth factor (VEGF) therapy or …

Classification of diabetes-related retinal diseases using a deep learning approach in optical coherence tomography

O Perdomo, H Rios, FJ Rodríguez, S Otálora… - Computer methods and …, 2019 - Elsevier
Abstract Background and objectives: Spectral Domain Optical Coherence Tomography (SD-
OCT) is a volumetric imaging technique that allows measuring patterns between layers such …

[HTML][HTML] Cellular reparative mechanisms of mesenchymal stem cells for retinal diseases

SLS Ding, S Kumar, PL Mok - International Journal of Molecular Sciences, 2017 - mdpi.com
The use of multipotent mesenchymal stem cells (MSCs) has been reported as promising for
the treatment of numerous degenerative disorders including the eye. In retinal degenerative …

[HTML][HTML] Antioxidative activity of probiotics

A Hoffmann, P Kleniewska… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Probiotics are defined as live microorganisms that have a beneficial effect on health by
exhibiting quantitative and qualitative effects on intestinal microflora and/or modification of …

Ophthalmic magnetic resonance imaging: where are we (heading to)?

T Niendorf, JWM Beenakker, S Langner… - Current eye …, 2021 - Taylor & Francis
Magnetic resonance imaging of the eye and orbit (MReye) is a cross-domain research field,
combining (bio) physics,(bio) engineering, physiology, data sciences and ophthalmology. A …

[HTML][HTML] GABNet: global attention block for retinal OCT disease classification

X Huang, Z Ai, H Wang, C She, J Feng, Q Wei… - Frontiers in …, 2023 - frontiersin.org
Introduction The retina represents a critical ocular structure. Of the various ophthalmic
afflictions, retinal pathologies have garnered considerable scientific interest, owing to their …

[HTML][HTML] Metformin, a potential role in age-related macular degeneration: a systematic review and meta-analysis

DF Romdhoniyyah, SP Harding, CP Cheyne… - Ophthalmology and …, 2021 - Springer
Background Currently, no generally approved medical treatment can delay the onset of age-
related macular degeneration (AMD) or slow the progression of degenerative changes …

Risuteganib—a novel integrin inhibitor for the treatment of non-exudative (dry) age-related macular degeneration and diabetic macular edema

LT Shaw, A Mackin, R Shah, S Jain, P Jain… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Non-exudative (dry) age-related macular degeneration (AMD) and diabetic
macular edema (DME) are leading causes of vision loss worldwide. Besides age-related …