The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Abnormal vasculature is one of the most conspicuous traits of tumor tissue, largely
contributing to tumor immune evasion. The deregulation mainly arises from the potentiated …

Metastatic progression combined with non-responsiveness towards systemic therapy often
shapes the course of disease for cancer patients and commonly determines its lethal …

The current study investigated the cytotoxic effect of ten sulfonamide-derived isatins,
following molecular hybridization, based on the association principles, on hepatocellular …

Heparan sulfate proteoglycans (HSPGs) mediate essential interactions throughout the
extracellular matrix (ECM), providing signals that regulate cellular growth and development …

Marine natural products are a discerning arena to search for the future generation of
medications to treat a spectrum of ailments. Meanwhile, cancer is becoming more ubiquitous …

Neutrophils play a vital role in the formation of arterial, venous and cancer-related
thrombosis. Recent studies have shown that in a process known as NETosis, neutrophils …

The tumor microenvironment (TME) components play a crucial role in cancer cells'
resistance to chemotherapeutic agents. This phenomenon is exceptionally fundamental in …

Mammalian glycosaminoglycans (GAGs), except hyaluronan (HA), are sulfated
polysaccharides that are covalently attached to core proteins to form proteoglycans (PGs) …

The aim of this paper is to offer a narrative review of the literature regarding the influence of
transition metals on angiogenesis, excluding lanthanides and actinides. To our knowledge …