The “rights” of precision drug development for Alzheimer's disease

J Cummings, HH Feldman, P Scheltens - Alzheimer's research & therapy, 2019 - Springer
There is a high rate of failure in Alzheimer's disease (AD) drug development with 99% of
trials showing no drug-placebo difference. This low rate of success delays new treatments …

[HTML][HTML] Recruitment and retention of underrepresented populations in Alzheimer's disease research: a systematic review

AL Gilmore-Bykovskyi, Y Jin, C Gleason… - Alzheimer's & Dementia …, 2019 - Elsevier
Introduction Alzheimer's disease and related dementias (ADRD) disproportionately impact
racial and ethnic minority and socioeconomically disadvantaged adults. Yet, these …

[HTML][HTML] Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: update and areas of immediate need

GM Babulal, YT Quiroz, BC Albensi… - Alzheimer's & …, 2019 - Elsevier
Alzheimer's disease and related dementias (ADRDs) are a global crisis facing the aging
population and society as a whole. With the numbers of people with ADRDs predicted to rise …

Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation

JC Lennon, SL Aita, VAD Bene, T Rhoads… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Although dementia prevalence differs by race, it remains unclear whether
cognition and neuropsychiatric symptom severity differ between Black and White individuals …

[HTML][HTML] Intersectionality in Alzheimer's disease: the role of female sex and Black American race in the development and prevalence of Alzheimer's disease

MB Misiura, B Butts, B Hammerschlag, C Munkombwe… - …, 2023 - Elsevier
It is well known that vascular factors and specific social determinants of health contribute to
dementia risk and that the prevalence of these risk factors differs according to race and sex …

Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers

M Berger, JN Browndyke… - Annals of clinical …, 2022 - Wiley Online Library
Objective Numerous investigators have theorized that postoperative changes in Alzheimer's
disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we …

Perspective on the “African American participation in Alzheimer disease research: Effective strategies” workshop, 2018

A Denny, M Streitz, K Stock… - Alzheimer's & …, 2020 - Wiley Online Library
Abstract The Washington University School of Medicine Knight Alzheimer Disease Research
Center's “African American Participation in Alzheimer Disease Research: Effective …

Effects of sex, race, ethnicity, and education on online aging research participation

MT Ashford, J Eichenbaum, T Williams… - … Research & Clinical …, 2020 - Wiley Online Library
Introduction This study aimed to identify the relationship of sociodemographic variables with
older adults participation in an online registry for recruitment and longitudinal assessment in …

Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI)

MT Ashford, R Raman, G Miller… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction An analysis of the ethnocultural and socioeconomic composition of Alzheimer's
Disease Neuroimaging Initiative (ADNI) participants is needed to assess the generalizability …

Development and implementation of an electronic clinical dementia rating and financial capacity instrument‐short form

T Howell, S Gummadi, C Bui… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction To address the need for remote assessments of cognitive decline and dementia,
we developed and administered electronic versions of the Clinical Dementia Rating (CDR®) …