DFT Computational Studies, Spectroscopic (UV–Vis, IR, NMR), In Silico Molecular Docking and ADME Study of 3-(3-Methylpyridin-2-yl)-5-phenyl-1, 2, 4-oxadiazole
RH Waghchaure, VA Adole - Journal of Molecular Structure, 2024 - Elsevier
In the current research, we used experimental and computational methods to examine the
structural, electronic, chemical, and biological behavior of 3-(3-methylpyridin-2-yl)-5-phenyl …
structural, electronic, chemical, and biological behavior of 3-(3-methylpyridin-2-yl)-5-phenyl …
Eco‐friendly approaches to 1, 3, 4‐oxadiazole derivatives: A comprehensive review of green synthetic strategies
D Shah, A Patel - Archiv der Pharmazie, 2024 - Wiley Online Library
This review article offers an environmentally benign synthesis of 1, 3, 4‐oxadiazole
derivatives, with a focus on sustainable methodologies that have minimal impact on the …
derivatives, with a focus on sustainable methodologies that have minimal impact on the …
Modes of action of a novel c-myc inhibiting 1, 2, 4-oxadiazole derivative in leukemia and breast cancer cells
The c-MYC oncogene regulates multiple cellular activities and is a potent driver of many
highly aggressive human cancers, such as leukemia and triple-negative breast cancer. The …
highly aggressive human cancers, such as leukemia and triple-negative breast cancer. The …
Design and Synthesis of 3-(2H-Chromen-3-yl)-5-aryl-1,2,4-oxadiazole Derivatives as Novel Toll-like Receptor 2/1 Agonists That Inhibit Lung Cancer In Vitro and In …
Y Wang, X Cheng, X Liu, J Xu, L Wang… - Journal of Medicinal …, 2024 - ACS Publications
Toll-like receptor (TLR) 2 is a transmembrane receptor that participates in the innate immune
response by forming a heterodimer with TLR1 or TLR6. TLR2 agonists play an important …
response by forming a heterodimer with TLR1 or TLR6. TLR2 agonists play an important …
Tertiary Amines as Temporary Masked Secondary Amines: A Direct Access to 5-Dialkylamino-1, 2, 4-oxadiazoles from 1, 2, 4-Oxadiazol-5 (4H)-ones
M Alfliadhi, M Pattarawarapan, S Hongsibsong… - …, 2024 - thieme-connect.com
A novel strategy utilizing tertiary amines as temporary masked secondary amines to
synthesize 5-dialkylamino 1, 2, 4-oxadiazoles via Ph 3 PI 2 mediated amination of 1, 2, 4 …
synthesize 5-dialkylamino 1, 2, 4-oxadiazoles via Ph 3 PI 2 mediated amination of 1, 2, 4 …
N-Arylamino-1,2,4-oxadiazol-5(4H)-ones: Synthesis, Luminescent, Antibacterial, and Antienteroviral Properties
AS Konstantinova, AA Shetnev, AV Semenov… - Russian Journal of …, 2024 - Springer
Method for the preparation of N-arylamino-1, 2, 4-oxadiazol-5 (4 H)-ones via reduction of N-
nitrophenyl-1, 2, 4-oxadiazol-5 (4 H)-ones with tin (II) chloride has been developed. The …
nitrophenyl-1, 2, 4-oxadiazol-5 (4 H)-ones with tin (II) chloride has been developed. The …
Small molecules targeting apoptosis and parthanatos in sensitive and drug-resistant tumor cells
M Zhou - 2023 - openscience.ub.uni-mainz.de
Resisting cell death is one of the hallmarks of carcinogenesis, especially when it is relevant
to tumor proliferation pathways and oncogene overexpression. Deregulation of cell death …
to tumor proliferation pathways and oncogene overexpression. Deregulation of cell death …