Identification and validation of key genes associated with non‐small‐cell lung cancer

Q Ma, Y Xu, H Liao, Y Cai, L Xu, D Xiao… - Journal of cellular …, 2019 - Wiley Online Library
Non‐small‐cell lung cancer (NSCLC) is one of the main causes of death induced by cancer
globally. However, the molecular aberrations in NSCLC patients remain unclearly. In the …

Interaction between DNMT3B and MYH11 via hypermethylation regulates gastric cancer progression

J Wang, P Xu, Y Hao, T Yu, L Liu, Y Song, Y Li - BMC cancer, 2021 - Springer
Background Gastric cancer (GC) has an unwelcoming prognosis when diagnosed at an
advanced stage. The purpose of this study was to examine the expression of myosin heavy …

Unlocking the potential: A novel prognostic index signature for acute myeloid leukemia

LQ Zhang, YC Liang, JX Wang, J Zhang, T La… - Computers in Biology …, 2024 - Elsevier
Acute myeloid leukemia (AML) is an aggressive malignancy characterized by challenges in
treatment, including drug resistance and frequent relapse. Recent research highlights the …

Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma

W Wang, C Wei, P Li, L Wang, W Li, K Chen, J Zhang… - Gene, 2018 - Elsevier
Abstract Systems biology approaches can help understand pathogenesis of complex human
diseases like cancers for identification of potential new therapeutic targets. Here in this …

N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT …

D Wen, H Xiao, Y Gao, H Zeng, J Deng - Molecular Cancer, 2024 - Springer
Background Elevated evidence suggests that the SENPs family plays an important role in
tumor progression. However, the role of SENPs in AML remains unclear. Methods We …

CBFB break-apart FISH testing: an analysis of 1629 AML cases with a focus on atypical findings and their implications in clinical diagnosis and management

RK Yang, GA Toruner, W Wang, H Fang, GC Issa… - Cancers, 2021 - mdpi.com
Simple Summary The inv (16)/t (16; 16) AML is a disease that is considered relatively easy
and straightforward to be diagnosed in the clinical laboratories. Up to date, CBFB FISH …

Identification of a two metastasis-related prognostic signature in the process of predicting the survival of laryngeal squamous cell carcinoma

Y Zheng, J Wu, B Yan, Y Yang, H Zhong, W Yi… - Scientific Reports, 2023 - nature.com
Metastasis is a major cause of treatment failure and poor outcomes in cancer patients. The
data used in the current study was downloaded from TCGA and GEO databases …

Somatic mutations of activating signalling, transcription factor, and tumour suppressor are a precondition for leukaemia transformation in myelodysplastic syndromes

F Xu, LY Wu, J Guo, Q He, Z Zhang… - Journal of Cellular and …, 2022 - Wiley Online Library
The transformation biology of secondary acute myeloid leukaemia (AML) from
myelodysplastic syndromes (MDSs) is still not fully understood. We performed paired self …

Integrative immunophenotypic and genetic characterization of acute myeloid leukemia with CBFB rearrangement

F Sameeta, SA Wang, Z Tang, JD Khoury… - American Journal of …, 2024 - academic.oup.com
Objectives We sought to characterize the immunophenotype of acute myeloid leukemia
(AML) with CBFB rearrangement and correlate the results with cytogenetic and molecular …

The identification of key gene expression signature in prostate cancer

Y Huang, Q Cao, Z Song, H Ruan… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Prostate cancer (PCa) is one of the most common malignancies affecting men's health
worldwide. The aim of this study is to identify key genes and their regulatory networks and …