Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges
RA Wilke, DW Lin, DM Roden, PB Watkins… - Nature reviews Drug …, 2007 - nature.com
Serious adverse drug reactions (SADRs) are a major cause of morbidity and mortality
worldwide. Some SADRs may be predictable, based upon a drug's pharmacodynamic and …
worldwide. Some SADRs may be predictable, based upon a drug's pharmacodynamic and …
Muscle toxicity of drugs: when drugs turn physiology into pathophysiology
L Janssen, NAE Allard, CGJ Saris… - Physiological …, 2020 - journals.physiology.org
Drugs are prescribed to manage or prevent symptoms and diseases, but may sometimes
cause unexpected toxicity to muscles. The symptomatology and clinical manifestations of the …
cause unexpected toxicity to muscles. The symptomatology and clinical manifestations of the …
A stability-indicating high performance liquid chromatographic (HPLC) assay for the simultaneous determination of atorvastatin and amlodipine in commercial tablets
A Mohammadi, N Rezanour, MA Dogaheh… - … of chromatography B, 2007 - Elsevier
A simple, rapid, precise and accurate isocratic reversed-phase stability-indicating HPLC
method was developed and validated for the simultaneous determination of atorvastatin (AT) …
method was developed and validated for the simultaneous determination of atorvastatin (AT) …
Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography–electrospray ionization tandem mass spectrometry
XS Miao, CD Metcalfe - Journal of Chromatography A, 2003 - Elsevier
Cholesterol-lowering statin drugs are among the most frequently prescribed agents for
reducing morbidity and mortality related to coronary heart disease. Four major statin drugs …
reducing morbidity and mortality related to coronary heart disease. Four major statin drugs …
Determination of atorvastatin in human serum by reversed-phase high-performance liquid chromatography with UV detection
G Bahrami, B Mohammadi, S Mirzaeei… - Journal of Chromatography …, 2005 - Elsevier
A rapid and sensitive high-performance liquid chromatographic method was validated and
described for determination of atorvastatin in human serum. Following liquid–liquid …
described for determination of atorvastatin in human serum. Following liquid–liquid …
Fabrication of a TiO 2 and clay nanoparticle composite electrode as a sensor
SD Bukkitgar, NP Shetti - Analytical methods, 2017 - pubs.rsc.org
In the present study, a simple, selective, and sensitive electrochemical method for the
determination of atorvastatin was proposed based on a composite electrode. The electrode …
determination of atorvastatin was proposed based on a composite electrode. The electrode …
Pharmacokinetics of atorvastatin and its metabolites after single and multiple dosing in hypercholesterolaemic haemodialysis patients
RL Lins, KE Matthys, GA Verpooten… - Nephrology Dialysis …, 2003 - academic.oup.com
Background. Patients with chronic renal failure commonly suffer from a secondary form of
complex dyslipidaemia, and may benefit from lipid‐lowering treatment. Atorvastatin has …
complex dyslipidaemia, and may benefit from lipid‐lowering treatment. Atorvastatin has …
[HTML][HTML] Graphene sheet-based electrochemical sensor with cationic surfactant for sensitive detection of atorvastatin
The present work investigates the electrochemical studies of atorvastatin (ATRV) by
establishing graphene (GR) and cationic surfactant cetyltrimethylammonium bromide …
establishing graphene (GR) and cationic surfactant cetyltrimethylammonium bromide …
Construction of nanoparticles composite sensor for atorvastatin and its determination in pharmaceutical and urine samples
In the present work, first time a composite electrode based on nano-silica and zinc oxide
nanoparticles were investigated for electrochemical determination of atorvastatin. The …
nanoparticles were investigated for electrochemical determination of atorvastatin. The …
HPLC methods for the determination of simvastatin and atorvastatin
L Nováková, D Šatínský, P Solich - TrAC Trends in Analytical Chemistry, 2008 - Elsevier
We review high-performance liquid chromatography (HPLC) methods for the determination
of two major statins used in clinical treatment–simvastatin and atorvastatin–in various fields …
of two major statins used in clinical treatment–simvastatin and atorvastatin–in various fields …