Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

It is estimated that 2% to 3% of the population are currently prescribed systemic or topical
glucocorticoid treatment. The potent anti-inflammatory action of glucocorticoids to deliver …

The discovery of ketamine as a rapid-acting antidepressant spurred significant research to
understand its underlying mechanisms of action and to identify other novel compounds that …

Bipolar disorder is a decidedly heterogeneous and multifactorial disease, with a high
individual and societal burden. While not all patients display overt markers of elevated …

Inflammatory bowel disease (IBD) is complex, chronic, and relapsing gastrointestinal
inflammatory disorders, which includes mainly two conditions, namely ulcerative colitis (UC) …

Psychedelics are increasingly being recognized for their potential to treat a wide range of
brain disorders including depression, post‐traumatic stress disorder (PTSD), and substance …

Accumulating clinical evidence shows that psychedelic therapy, by synergistically combining
psychopharmacology and psychological support, offers a promising transdiagnostic …

Type 2 immunity helps protect the host from infection, but it also plays key roles in tissue
homeostasis, metabolism, and repair. Unfortunately, inappropriate type 2 immune reactions …