Role of T-lymphocytes and pro-inflammatory mediators in the pathogenesis of chronic obstructive pulmonary disease

A Gadgil, SR Duncan - International journal of chronic obstructive …, 2008 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the
US and a major worldwide healthcare problem. The pathophysiologic mechanisms that …

Impact of medical comorbid disease on antidepressant treatment of major depressive disorder

DV Iosifescu, B Bankier, M Fava - Current Psychiatry Reports, 2004 - Springer
A major factor in evaluating and treating depression is the presence of comorbid medical
problems. In this paper, the authors will first evaluate studies showing that medical illness is …

The impact of medical comorbidity on acute treatment in major depressive disorder

DV Iosifescu, AA Nierenberg, JE Alpert, M Smith… - Focus, 2005 - psychiatryonline.org
Objective: The authors investigated the impact of medical comorbidity on the acute phase of
antidepressant treatment in subjects with major depressive disorder. Method: A total of 384 …

Glucagon-like peptide-1 receptor (GLP-1R) signaling ameliorates dysfunctional immunity in COPD patients

J Huang, H Yi, C Zhao, Y Zhang, L Zhu… - … journal of chronic …, 2018 - Taylor & Francis
Background The glucagon-like peptide-1 receptor (GLP-1R) agonist–liraglutide (LIR)–is an
insulin secretagogue for the treatment of diabetes and has been proven to have therapeutic …

Współistnienie chorób somatycznych i depresji

D Dudek, M Siwek - Psychiatria, 2007 - journals.viamedica.pl
Artykuł stanowi przegląd zagadnień dotyczących współwystępowania zaburzeń
depresyjnych oraz poważnych schorzeń somatycznych. Autorzy omówili między innymi …

Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models

M Lucattelli, B Bartalesi, E Cavarra, S Fineschi… - Respiratory …, 2005 - Springer
Background The separation of emphysema from fibrosis is not as clear-cut as it was thought
in early studies. These two pathologies may be present at the same time in human lungs …

Treating depression in the medically ill

DV Iosifescu - Psychiatric Clinics of North America, 2007 - Elsevier
This article assesses the course of depressive disorders in persons who have comorbid
medical illness. The article reviews a series of randomized, controlled studies of …

Analysis of the bacterial community in chronic obstructive pulmonary disease sputum samples by denaturing gradient gel electrophoresis and real-time PCR

D Wu, C Hou, Y Li, Z Zhao, J Liu, X Lu, X Shang… - BMC Pulmonary …, 2014 - Springer
Abstract Background The Global Initiative defines COPD for chronic obstructive lung disease
as an entirely preventable and treatable disease characterized by sputum production …

[HTML][HTML] Mixed infections with Porphyromonas gingivalis and Treponema denticola cause excessive inflammatory responses in a mouse pneumonia model compared …

R Kimizuka, T Kato, K Ishihara, K Okuda - Microbes and infection, 2003 - Elsevier
Periodontopathic anaerobes such as Porphyromonas gingivalis are frequently found in
aspiration pneumonia and lung abscesses. However, defense mechanisms and responses …

Integrins in pulmonary inflammatory diseases

S Bazan-Socha, A Bukiej… - Current …, 2005 - ingentaconnect.com
Integrins are a family of heterodimeric transmembrane glycoproteins that mediate cell-cell
and cell-matrix interactions. They participate in inflammatory reactions mainly by regulation …