[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers

CH Lin, CH Chen, ZC Lin, JY Fang - Journal of food and drug analysis, 2017 - Elsevier
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …

[PDF][PDF] Oxidative stress associated with SARS-Cov-2 (COVID-19) increases the severity of the lung disease-a systematic review

S Derouiche - J Infect Dis Epidemiol, 2020 - researchgate.net
COVID-19 patients have a higher risk of developing inflammatory responses associated with
serious and even fatal respiratory diseases. This review focuses on the relationship between …

Exploring recent developments to improve antioxidant, anti-inflammatory and antimicrobial efficacy of curcumin: A review of new trends and future perspectives

Z Hussain, HE Thu, MW Amjad, F Hussain… - Materials science and …, 2017 - Elsevier
Curcumin derivatives have been well-documented due to their natural antioxidant,
antimicrobial and anti-inflammatory activities. Curcuminoids have also gained widespread …

LPS-induced murine neuroinflammation model: main features and suitability for pre-clinical assessment of nutraceuticals

M Nava Catorce, G Gevorkian - Current neuropharmacology, 2016 - ingentaconnect.com
Neuroinflammation is an important feature in the pathogenesis and progression of
neurodegenerative diseases such as Alzheimer´ s disease (AD), Parkinson´ s disease (PD) …

NF-κB-mediated neuroinflammation in Parkinson's disease and potential therapeutic effect of polyphenols

SS Singh, SN Rai, H Birla, W Zahra, AS Rathore… - Neurotoxicity …, 2020 - Springer
Different animal and human studies from last two decades in the case of Parkinson's
disease (PD) have concentrated on oxidative stress due to increased inflammation and …

[HTML][HTML] Use of curcumin, a natural polyphenol for targeting molecular pathways in treating age-related neurodegenerative diseases

P Maiti, GL Dunbar - International journal of molecular sciences, 2018 - mdpi.com
Progressive accumulation of misfolded amyloid proteins in intracellular and extracellular
spaces is one of the principal reasons for synaptic damage and impairment of neuronal …

Polyphenols as potential metal chelation compounds against Alzheimer's disease

J Lakey-Beitia, AM Burillo, G La Penna… - Journal of …, 2021 - content.iospress.com
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …

Curcumin encapsulation in zein-rhamnolipid composite nanoparticles using a pH-driven method

L Dai, H Zhou, Y Wei, Y Gao, DJ McClements - Food Hydrocolloids, 2019 - Elsevier
Zein is widely used to encapsulate non-polar bioactives due to its ability to form protein
nanoparticles with hydrophobic interiors. In this study, a simple pH-driven method, which …

Curcumin encapsulated in milk exosomes resists human digestion and possesses enhanced intestinal permeability in vitro

M Vashisht, P Rani, SK Onteru, D Singh - Applied Biochemistry and …, 2017 - Springer
Exosomes, the extracellular secretary nano-vesicles, act as carriers of biomolecules to the
target cells. They exhibit several attributes of an efficient drug delivery system. Curcumin …

[HTML][HTML] Strategies for improving bioavailability, bioactivity, and physical-chemical behavior of curcumin

LZ Racz, CP Racz, LC Pop, G Tomoaia, A Mocanu… - Molecules, 2022 - mdpi.com
Curcumin (CCM) is one of the most frequently explored plant compounds with various
biological actions such as antibacterial, antiviral, antifungal, antineoplastic, and …