Therapeutic cancer vaccines: advancements, challenges, and prospects
T Fan, M Zhang, J Yang, Z Zhu, W Cao… - Signal Transduction and …, 2023 - nature.com
With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the …
cell therapies, cancer immunotherapy has undergone a profound transformation over the …
Biomaterials Facilitating Dendritic Cell‐Mediated Cancer Immunotherapy
Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …
prospects because DCs play a central role in initiating and regulating adaptive immune …
Dendritic Nanomedicine with Boronate Bonds for Augmented Chemo‐Immunotherapy via Synergistic Modulation of Tumor Immune Microenvironment
Y Li, Y Wu, Z Fang, Y Zhang, H Ding, L Ren… - Advanced …, 2024 - Wiley Online Library
Unsatisfied tumor accumulation of chemotherapeutic drugs and a complicated
immunosuppressive microenvironment diminish the immune response rate and the …
immunosuppressive microenvironment diminish the immune response rate and the …
Engineered living materials for advanced diseases therapy
X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …
Anti-tumor immune potentiation targets-engineered nanobiotechnologies: design principles and applications
R Jiao, X Lin, Q Zhang, Y Zhang, W Qin, Q Yang… - Progress in Materials …, 2023 - Elsevier
Combined therapeutic strategies hold promises in augmenting antigen release to enhance
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …
Engineering metal-based hydrogel-mediated tertiary lymphoid structure formation via activation of the STING pathway for enhanced immunotherapy
XK Jin, JL Liang, SM Zhang, P Ji, QX Huang… - Materials …, 2023 - pubs.rsc.org
Tertiary lymphoid structures (TLSs) primarily constructed by multiple immune cells can
effectively enhance tumor immune responses, but expediting the formation of TLSs is still an …
effectively enhance tumor immune responses, but expediting the formation of TLSs is still an …
Immunotherapy: cancer immunotherapy and its combination with nanomaterials and other therapies
Immunotherapy is a new type of tumor treatment after surgery, radiotherapy and
chemotherapy, which can be used to manage and destroy tumor cells through activating or …
chemotherapy, which can be used to manage and destroy tumor cells through activating or …
Zinc‐Organometallic Framework Vaccine Controlled‐Release Zn2+ Regulates Tumor Extracellular Matrix Degradation Potentiate Efficacy of Immunotherapy
L Ding, M Liang, Y Li, M Zeng, M Liu, W Ma… - Advanced …, 2023 - Wiley Online Library
Tumor extracellular matrix (ECM) not only forms a physical barrier for T cells infiltration, but
also regulates multiple immunosuppressive pathways, which is an important reason for …
also regulates multiple immunosuppressive pathways, which is an important reason for …
Antigen Self-Presented Personalized Nanovaccines Boost the Immunotherapy of Highly Invasive and Metastatic Tumors
T Wang, M Han, Y Han, Z Jiang, Q Zheng, H Zhang… - ACS …, 2024 - ACS Publications
Dendritic cell (DC)-based vaccines have shown promise in adoptive cell therapy for
enhancing the antigen-specific response of antitumor immunity. However, their clinical …
enhancing the antigen-specific response of antitumor immunity. However, their clinical …
Carrier-free nanovaccine: An innovative strategy for ultrahigh melanoma neoantigen loading
T Zeng, W Zang, H Xiao, Y Jiang, S Lin, M Wang, S Li… - ACS …, 2023 - ACS Publications
In personalized cancer immunotherapy, developing an effective neoantigen nanovaccine
with high immunogenicity is a significant challenge. Traditional nanovaccine delivery …
with high immunogenicity is a significant challenge. Traditional nanovaccine delivery …