[HTML][HTML] Autonomic regulation of brown adipose tissue thermogenesis in health and disease: potential clinical applications for altering BAT thermogenesis

D Tupone, CJ Madden, SF Morrison - Frontiers in neuroscience, 2014 - frontiersin.org
From mouse to man, brown adipose tissue (BAT) is a significant source of thermogenesis
contributing to the maintenance of the body temperature homeostasis during the challenge …

[HTML][HTML] Adiponectin and orexin-A as a potential immunity link between Adipose tissue and central nervous system

R Polito, E Nigro, A Messina, ML Monaco… - Frontiers in …, 2018 - frontiersin.org
Adipose tissue (AT) is strongly associated with development and progression of immune
disorders through adipokines secretion, such as adiponectin. This protein has beneficial …

[HTML][HTML] Neuroendocrine, autonomic, and metabolic responses to an orexin antagonist, suvorexant, in psychiatric patients with insomnia

M Nakamura, T Nagamine - Innovations in clinical neuroscience, 2017 - ncbi.nlm.nih.gov
Aim: The aim of this study was to investigate the neuroendocrine, autonomic, and metabolic
system responses to suvorexant in psychiatric subjects with insomnia. Design: This …

Effects of a maternal high-fat diet on offspring behavioral and metabolic parameters in a rodent model

SA Johnson, AB Javurek, MS Painter… - … origins of health and …, 2017 - cambridge.org
Maternal diet-induced obesity can cause detrimental developmental origins of health and
disease in offspring. Perinatal exposure to a high-fat diet (HFD) can lead to later behavioral …

Orexin 2 receptor regulation of the hypothalamic–pituitary–adrenal (HPA) response to acute and repeated stress

LA Grafe, D Eacret, S Luz, AL Gotter, JJ Renger… - Neuroscience, 2017 - Elsevier
Orexins are hypothalamic neuropeptides that have a documented role in mediating the
acute stress response. However, their role in habituation to repeated stress, and the role of …

Melatonin treatment suppresses appetite genes and improves adipose tissue plasticity in diet-induced obese zebrafish

G Montalbano, M Mania, F Abbate, M Navarra… - Endocrine, 2018 - Springer
Purpose Overweight and obesity are important risk factors for diabetes, cardiovascular
diseases, and premature death in modern society. Recently, numerous natural and synthetic …

Hypothalamic dysfunction in obesity and metabolic disorders

S Carmo-Silva, C Cavadas - Obesity and brain function, 2017 - Springer
The hypothalamus is the brain region responsible for the maintenance of energetic
homeostasis. The regulation of this process arises from the ability of the hypothalamus to …

Sex-dependent effects of developmental exposure to bisphenol A and ethinyl estradiol on metabolic parameters and voluntary physical activity

SA Johnson, MS Painter, AB Javurek… - … origins of health and …, 2015 - cambridge.org
Endocrine disrupting chemicals (EDC) have received considerable attention as potential
obesogens. Past studies examining obesogenic potential of one widespread EDC …

[HTML][HTML] Impaired hormonal regulation of appetite in schizophrenia: a narrative review dissecting intrinsic mechanisms and the effects of antipsychotics

M Lis, B Stańczykiewicz, P Liśkiewicz… - Psychoneuroendocrinology, 2020 - Elsevier
Cardiometabolic diseases are the main contributor of reduced life expectancy in patients
with schizophrenia. It is now widely accepted that antipsychotic treatment plays an important …

[HTML][HTML] Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice

E Dickson, R Soylu-Kucharz, Å Petersén… - Molecular Metabolism, 2022 - Elsevier
Abstract Objective In Huntington's disease (HD), the disease-causing huntingtin (HTT)
protein is ubiquitously expressed and causes both central and peripheral pathology. In …