Nuclear factor erythroid 2-related factor 2 (Nrf2) is a powerful nuclear transcription factor that
coordinates an antioxidant cytoprotector system complex stimulated by the increase in …

If genetics defines the inheritance of DNA, epigenetics aims to regulate and make it
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …

Paternal pre-conceptual environmental experiences, such as stress and diet, can affect
offspring brain and behavioral phenotypes via epigenetic modifications in sperm …

The polygenic nature of neurological and psychiatric syndromes and the significant impact
of environmental factors on the underlying developmental, homeostatic, and neuroplastic …

Background Although in all sexually reproducing organisms an individual has a mother and
a father, non-genetic inheritance has been predominantly studied in mothers. Paternal …

Physical exercise not only helps to improve physical health but can also enhance brain
development and cognition. Recent reports on parental (both maternal and paternal) effects …

A significant number of studies have demonstrated that paternal exercise modulates future
generations via effects on the sperm epigenome. However, comprehensive information …

Exercise is a well-known non-pharmacologic agent used to prevent and treat a wide range
of pathologic conditions such as metabolic and cardiovascular disease. In this sense, the …

Recent studies on intergenerational transmission of learning and memory performances
demonstrated that parental spatial training before fertilization could facilitate learning and …

Maternal deprivation (MD) leads to long-lasting memory deficits. Conversely, maternal
exercise could potently modify the offspring's cellular machinery. Here, we tested whether …