Efficacy of anti‐inflammatory treatment on major depressive disorder or depressive symptoms: meta‐analysis of clinical trials

O Köhler‐Forsberg, C N. Lydholm… - Acta Psychiatrica …, 2019 - Wiley Online Library
Background No study has gathered evidence from all randomized clinical trials (RCT s) with
anti‐inflammatory drugs measuring antidepressant effects including a detailed assessment …

Anti-inflammatory treatments for mood disorders: systematic review and meta-analysis

MI Husain, R Strawbridge… - Journal of …, 2017 - journals.sagepub.com
Background: Recent studies suggest that anti-inflammatory medication may play a role in
the treatment of mood disorders. Aims: The purpose of this study was to determine the …

[HTML][HTML] Celecoxib for mood disorders: a systematic review and meta-analysis of randomized controlled trials

A Gędek, Z Szular, AZ Antosik, P Mierzejewski… - Journal of Clinical …, 2023 - mdpi.com
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory
parameters have not yet been comprehensively evaluated. The aim of this study was to …

[HTML][HTML] Comparison of saffron versus fluoxetine in treatment of mild to moderate postpartum depression: a double-blind, randomized clinical trial

L Kashani, S Eslatmanesh, N Saedi… - …, 2017 - thieme-connect.com
Introduction: Postpartum depression is a common mental health problem that is associated
with maternal suffering. The aim of this double-blind clinical trial was to compare safety and …

[HTML][HTML] Neurobiology and therapeutic potential of cyclooxygenase-2 (COX-2) inhibitors for inflammation in neuropsychiatric disorders

R Sethi, N Gómez-Coronado, AJ Walker… - Frontiers in …, 2019 - frontiersin.org
Neuropsychiatric disorders, such as depression, bipolar disorder, schizophrenia, obsessive-
compulsive disorder, and neurodevelopmental disorders such as autism spectrum disorder …

Modulating neuroinflammation to treat neuropsychiatric disorders

FA Radtke, G Chapman, J Hall… - BioMed research …, 2017 - Wiley Online Library
Neuroinflammation is recognised as one of the potential mechanisms mediating the onset of
a broad range of psychiatric disorders and may contribute to nonresponsiveness to current …

Therapeutic effects of minocycline on mild-to-moderate depression in HIV patients: a double-blind, placebo-controlled, randomized trial

H Emadi-Kouchak, P Mohammadinejad… - International clinical …, 2016 - journals.lww.com
Patients with the HIV infection are at high risk for developing depression. The aim of this
study was to investigate the safety and efficacy of antidepressant effects of minocycline on …

[HTML][HTML] Current perspectives on pharmacological and non-pharmacological interventions for the inflammatory mechanism of unipolar depression

IA Dogaru, MG Puiu, M Manea, V Dionisie - Brain Sciences, 2022 - mdpi.com
Since depression remains a major public health issue there is a constant need for new and
more efficient therapeutic strategies based on the mechanisms involved in the aetiology of …

[HTML][HTML] Effect of celecoxib on improving depression: A systematic review and meta-analysis

Z Wang, Q Wu, Q Wang - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
BACKGROUND Anti-inflammation drugs were uncovered to be a potential therapy for
depression. Celecoxib as a selective COX2 inhibitor is also one anti-inflammation drugs …

Cool the Inflamed Brain: A Novel Anti-inflammatory Strategy for the Treatment of Major Depressive Disorder

WJ Su, T Hu, CL Jiang - Current Neuropharmacology, 2024 - ingentaconnect.com
Background: Abundant evidence suggests that inflammatory cytokines contribute to the
symptoms of major depressive disorder (MDD) by altering neurotransmission …