Deciphering the role of neddylation in tumor microenvironment modulation: common outcome of multiple signaling pathways

D Liu, X Che, G Wu - Biomarker Research, 2024 - Springer
Neddylation is a post-translational modification process, similar to ubiquitination, that
controls several biological processes. Notably, it is often aberrantly activated in neoplasms …

Targeting Apoptosis in AML: Where Do We Stand?

K Krawiec, P Strzałka, M Czemerska, A Wiśnik, I Zawlik… - Cancers, 2022 - mdpi.com
Simple Summary In patients with acute myeloid leukemia (AML), genetic mutations can
cause cells to evade regulated cell death (RCD), resulting in excessive cell proliferation. The …

CircRNAs as new therapeutic entities and tools for target identification in Acute myeloid leukemia

A Nopora, UH Weidle - Cancer Genomics & Proteomics, 2024 - cgp.iiarjournals.org
Acute myeloid leukemia (AML) is a genetically extremely heterogeneous disease. Drug
resistance after induction therapy is a very frequent event resulting in poor medium survival …

[HTML][HTML] Personalizing precision medicine: Patients with AML perceptions about treatment decisions

Å Grauman, M Kontro, K Haller, S Nier, S Aakko… - Patient Education and …, 2023 - Elsevier
Background This study aims to explore patients' with acute myeloid leukemia perceptions
about precision medicine and their preferences for involvement in this new area of shared …

Distinct N7-methylguanosine profiles of circular RNAs in drug-resistant acute myeloid leukemia

J Fu, L Si, Y Zhou, D Li, R Wang - Scientific Reports, 2023 - nature.com
Post-transcriptional methylation modifications, such as the N7-methylguanosine (m7G)
modification, are increasingly acknowledged for their role in the development and resistance …

SLC25A1-associated prognostic signature predicts poor survival in acute myeloid leukemia patients

F Liu, S Deng, Y Li, J Du, H Zeng - Frontiers in Genetics, 2023 - frontiersin.org
Background: Acute myeloid leukemia (AML) is a heterogeneous malignant disease.
SLC25A1, the gene encoding mitochondrial carrier subfamily of solute carrier proteins, was …

MT1E in AML: a gateway to understanding regulatory cell death and immunotherapeutic responses

X Zhuang, P Chen, K Yang, R Yang… - Journal of Leukocyte …, 2024 - academic.oup.com
Regulated cell death (RCD) plays a crucial role in the initiation and progression of tumors,
particularly in acute myeloid leukemia (AML). This study investigates the prognostic …

60 yaş ve üzeri AML olgularının klinik, demografik, prognostik verilerinin tedavi rejimlerinin ve yanıtlarının retrospektif incelenmesi

M Mammacioğlu - 2022 - search.proquest.com
Abstract GİRİŞ VE AMAÇ: Akut lösemiler hematopoietik prekürsör hücrelerin klonal
proliferasyonuyla karakterize agresif malignitelerdir. Bir kısım ileri yaş AML hastaları yüksek …