Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
H Döhner, E Estey, D Grimwade… - Blood, The Journal …, 2017 - ashpublications.org
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and
management of acute myeloid leukemia (AML) in adults, published in 2010, has found …
management of acute myeloid leukemia (AML) in adults, published in 2010, has found …
Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance
D Grimwade, A Ivey, BJP Huntly - Blood, The Journal of the …, 2016 - ashpublications.org
Recent major advances in understanding the molecular basis of acute myeloid leukemia
(AML) provide a double-edged sword. Although defining the topology and key features of …
(AML) provide a double-edged sword. Although defining the topology and key features of …
A 17-gene stemness score for rapid determination of risk in acute leukaemia
SWK Ng, A Mitchell, JA Kennedy, WC Chen, J McLeod… - Nature, 2016 - nature.com
Refractoriness to induction chemotherapy and relapse after achievement of remission are
the main obstacles to cure in acute myeloid leukaemia (AML). After standard induction …
the main obstacles to cure in acute myeloid leukaemia (AML). After standard induction …
[HTML][HTML] Acute myeloid leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Acute myeloid leukaemia (AML) incidence is age dependent, rising markedly in patients
aged! 60 years. Ageing of the European population may therefore contribute to the reported …
aged! 60 years. Ageing of the European population may therefore contribute to the reported …
Assessment of minimal residual disease in standard-risk AML
A Ivey, RK Hills, MA Simpson… - … England Journal of …, 2016 - Mass Medical Soc
Background Despite the molecular heterogeneity of standard-risk acute myeloid leukemia
(AML), treatment decisions are based on a limited number of molecular genetic markers and …
(AML), treatment decisions are based on a limited number of molecular genetic markers and …
Acute myeloid leukaemia
A Khwaja, M Bjorkholm, RE Gale, RL Levine… - Nature reviews Disease …, 2016 - nature.com
Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived
from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of …
from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of …
Allogeneic hematopoietic cell transplantation for acute myeloid leukemia: time to move toward a minimal residual disease–based definition of complete remission?
Purpose Patients with acute myeloid leukemia (AML) who are in morphologic complete
remission are typically considered separately from patients with active disease (ie,≥ 5 …
remission are typically considered separately from patients with active disease (ie,≥ 5 …
One million haemopoietic stem-cell transplants: a retrospective observational study
A Gratwohl, MC Pasquini, M Aljurf, Y Atsuta… - The Lancet …, 2015 - thelancet.com
Background The transplantation of cells, tissues, and organs has been recognised by WHO
as an important medical task for its member states; however, information about how to best …
as an important medical task for its member states; however, information about how to best …
Hematopoietic stem cell transplantation for patients with AML in first complete remission
JJ Cornelissen, D Blaise - Blood, The Journal of the American …, 2016 - ashpublications.org
Postremission therapy in patients with acute myeloid leukemia (AML) may consist of
continuing chemotherapy or transplantation using either autologous or allogeneic stem …
continuing chemotherapy or transplantation using either autologous or allogeneic stem …
Acute myeloid leukemia: 2014 Update on riskstratification and management
EH Estey - American journal of hematology, 2014 - Wiley Online Library
Overview: Evidence suggest that even patients aged 70 or above benefit from specific AML
therapy. The fundamental decision in AML then becomes whether to recommend standard …
therapy. The fundamental decision in AML then becomes whether to recommend standard …