Abstract Elevated lipoprotein (a)(Lp [a]) is a causal genetic risk factor for cardiovascular
disease. To determine if current evidence supports both screening and treatment for …

The pathogenesis of arterial thrombotic disease involves multiple genetic and environmental
factors related to atherosclerosis and thrombosis. Acute thrombosis at the site of a ruptured …

Context High levels of lipoprotein (a) are associated with increased risk of myocardial
infarction (MI). Objective To assess whether genetic data are consistent with this association …

Background An increased level of Lp (a) lipoprotein has been identified as a risk factor for
coronary artery disease that is highly heritable. The genetic determinants of the Lp (a) …

Objective—The aim of the present study was to determine whether lipoprotein (a)[Lp (a)],
considered a causal risk factor for cardiovascular disease, primarily promotes thrombosis or …

The aim of this review is to summarize present evidence of a causal association of
lipoprotein (a) with risk of ischemic heart disease (IHD). Evidence for causality includes …

Background The plasminogen (PLG) activation system is composed by a series of serine
proteases, inhibitors and several binding proteins, which together control the temporal and …

Purpose Cardiovascular (CV) diseases account for most worldwide mortality, and a higher
level of lipoprotein (Lp)-(a) is recognized as a prevalent contributing risk factor. However …

Abstract Lipoprotein (a)[Lp (a)] is an independent risk factor for atherosclerosis-related
events that is under strong genetic control (heritability= 0.68–0.98). However, causal …

Copy number variations (CNVs), genomic duplication or deletion events occurring at larger
than 1 kb scale, contribute to the complex diseases substantially. Lipoprotein (a)[Lp (a)] is a …