Pentanucleotide repeat polymorphism, lipoprotein (a) levels, and risk of ischemic heart disease
PR Kamstrup, A Tybjærg-Hansen… - The Journal of …, 2008 - academic.oup.com
Context: Lipoprotein (a) is a cardiovascular risk factor. Levels of lipoprotein (a) are
predominantly determined by apolipoprotein (a) gene variation, including a pentanucleotide …
predominantly determined by apolipoprotein (a) gene variation, including a pentanucleotide …
[HTML][HTML] Apo [a] size and PNR explain African American-Caucasian differences in allele-specific apo [a] levels for small but not large apo [a]
J Rubin, HJ Kim, TA Pearson, S Holleran… - Journal of lipid …, 2006 - ASBMB
Apolipoprotein [a](apo [a]) gene size is a major predictor of lipoprotein [a] level. To
determine genetic predictors of allele-specific apo [a] levels beyond gene size, we evaluated …
determine genetic predictors of allele-specific apo [a] levels beyond gene size, we evaluated …
A proximal tissue-specific module and a distal negative regulatory module control apolipoprotein (a) gene transcription
The apo (a)[apolipoprotein (a)] gene is responsible for variations in plasma lipoprotein (a),
high levels of which are a risk factor for atherosclerosis and myocardial infarction. The apo …
high levels of which are a risk factor for atherosclerosis and myocardial infarction. The apo …
[HTML][HTML] Association of the LPA gene polymorphisms with coronary artery disease risk in the Xinjiang population of China: A case–control study
YW Liu, CL Dong, X Jiang, DY Liu - Medicine, 2023 - journals.lww.com
Lipoprotein (a) is a well-known independent risk factor for coronary artery disease (CAD)
and primarily determined by variation in the LPA gene coding for the apolipoprotein (a) …
and primarily determined by variation in the LPA gene coding for the apolipoprotein (a) …
Elevated Lp (a) with a small apo (a) isoform in children: risk factor for the development of premature coronary artery disease
A Dirisamer, H Widhalm, E Aldover‐Macasaet… - Acta …, 2008 - Wiley Online Library
Background: levels of Lp (a) and low‐molecular‐weight apolipoprotein (a) isoform are
strongly associated with the development of early cardiovascular disease. Certain types of …
strongly associated with the development of early cardiovascular disease. Certain types of …
[HTML][HTML] A two-step genetic study on quantitative precursors of coronary artery disease in a homogeneous Indian population: Case–control association discovery and …
S Mallik, PP Majumder - Journal of biosciences, 2011 - Springer
In spite of its strong familiality, gene identification for coronary artery disease (CAD) has not
yielded a consistent picture. One major reason for this is that families or cases and controls …
yielded a consistent picture. One major reason for this is that families or cases and controls …
ALOX5, LPA, MMP9 and TPO gene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans
R Camacho-Mejorado, R Gómez… - Royal Society …, 2020 - royalsocietypublishing.org
Atherothrombosis is the cornerstone of cardiovascular diseases and the primary cause of
death worldwide. Genetic contribution to disturbances in lipid metabolism, coagulation …
death worldwide. Genetic contribution to disturbances in lipid metabolism, coagulation …
[HTML][HTML] A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave
C Lamina, M Haun, S Coassin, A Kloss-Brandstätter… - PLoS …, 2014 - journals.plos.org
Structural genetic variants as short tandem repeats (STRs) are not targeted in SNP-based
association studies and thus, their possible association signals are missed. We …
association studies and thus, their possible association signals are missed. We …
Relationship between plasma lipoprotein (a), apolipoprotein (a) phenotypes, and other coronary heart disease risk factors in a Melbourne South Asian population
ZW Xiong, ML Wahlqvist, TI Ibiebele, BM Biegler… - Clinical …, 2004 - Elsevier
Background: High plasma lipoprotein (a)[Lp (a)] level is a strong and important risk factor for
cardiovascular disease (CVD). Small-sized apolipoprotein (a)[apo (a)] isoforms (F, B, S1 …
cardiovascular disease (CVD). Small-sized apolipoprotein (a)[apo (a)] isoforms (F, B, S1 …
The apo (a) gene (TTTTA) n promoter polymorphism and its association with variability in exons of the kringle IV types 8 to 10
K Hirschfeldova, D Lipovska, P Skrha, R Ceska - Clinica Chimica Acta, 2009 - Elsevier
BACKGROUND: A large portion of lipoprotein (a) concentration is explained by the variable
number of kringle domains at the apo (a) gene. The (TTTTA) n repetition from the promoter …
number of kringle domains at the apo (a) gene. The (TTTTA) n repetition from the promoter …