CD4+ type 1 T regulatory (Tr1) cells have a crucial role in inducing tolerance. Immune
regulation by these cells is mainly mediated through the secretion of high amounts of IL-10 …

Triple negative breast cancer (TNBC) is a heterogenous disease often characterised by
aggressive biology and poor prognosis. Efforts to precisely treat TNBC have been …

Islands of CD123high cells have been commonly described in the bone marrow of patients
with chronic myelomonocytic leukemia (CMML). Using a multiparameter flow cytometry …

Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct
from classical dendritic cells. pDCs are generated in the bone marrow and following …

Dendritic cells (DCs) occupy a privileged position at the interface between innate and
adaptive immunity, orchestrating a large panel of responses to both physiological and …

Despite accumulating evidence suggesting a positive correlation between leptin levels,
obesity, post-menopause and breast cancer incidence, our current knowledge on the …

DCs play a pivotal role in orchestrating innate and adaptive antitumor immunity. Activated
DCs can produce large amounts of various proinflammatory cytokines, initiate T‐cell …

Cancer immunology is the most rapidly expanding field in cancer research, with the
importance of immunity in cancer pathogenesis now well accepted including in the …

Dendritic cells (DC) are key regulators of both innate and adaptive immunity, and the array
of immunoregulatory functions exhibited by these cells is dictated by their differentiation …

Cancer can be considered an aberrant organ with a hierarchical composition of different cell
populations. The tumor microenvironment, including the immune cells and related cytokines …