Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Polycaprolactone (PCL) is a polymer material suitable for being prepared into porous
scaffolds used in bone tissue engineering, however, insufficient osteogenic ability and …

This review focuses on understanding the macroscopic and microscopic characteristics of
bone tissue and reviews current knowledge of its physiology. It explores how these features …

The Wnt signalling pathway is one of the central signalling pathways in bone development,
homeostasis and regulation of bone mineral density. It consists of numerous Wnt ligands …

Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …

Hereditary metabolic bone diseases are characterized by genetic abnormalities in skeletal
homeostasis and encompass one of the most diverse groups among rare diseases. In this …

Mesenchymal stem cells (MSCs) have been identified in many adult tissues and they have
been closely studied in recent years, especially in view of their potential use for treating …

Hydrogels with long-term storage stability, controllable sustained-release properties, and
biocompatibility have been garnering attention as carriers for drug/growth factor delivery in …

Bone metabolism is a lifelong process that includes bone formation and resorption.
Osteoblasts and osteoclasts are the predominant cell types associated with bone …

Sufficient oxygen is required to maintain normal cellular and physiological function, such as
a creature's development, breeding, and homeostasis. Lately, some researchers have …