Regulatory mechanisms and regeneration strategies of the soft–hard tissue interface in the human periodontium

G Dang, Y Wei, Q Wan, J Gu, K Wang, M Wan… - …, 2024 - Wiley Online Library
The soft‐hard tissue interface of the human periodontium is responsible for periodontal
homeostasis and is essential for normal oral activities. This soft‐hard tissue interface is …

Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic‐Treated …

A Wallimann, W Magrath, B Pugliese… - Mediators of …, 2021 - Wiley Online Library
Short‐chain fatty acids (SCFAs) produced by the gut microbiota have previously been
demonstrated to play a role in numerous chronic inflammatory diseases and to be key …

Citrate zinc hydroxyapatite nanorods with enhanced cytocompatibility and osteogenesis for bone regeneration

MH Fernandes, MM Alves, M Cebotarenco… - Materials Science and …, 2020 - Elsevier
The development of biomaterials that mimicking the hydroxyapatite nanoparticles existent in
the immature bone tissue is crucial, especially to accelerate the bone remodeling and …

[HTML][HTML] Potential therapeutic applications of N-cadherin antagonists and agonists

OW Blaschuk - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
This review focuses on the cell adhesion molecule (CAM), known as neural (N)-cadherin
(CDH2). The molecular basis of N-cadherin-mediated intercellular adhesion is discussed, as …

Chitosan composite with mesenchymal stem cells: Properties, mechanism, and its application in bone regeneration

S Kudiyarasu, MKK Perumal, RR Renuka… - International Journal of …, 2024 - Elsevier
Bone defects resulting from trauma, illness or congenital abnormalities represent a
significant challenge to global health. Conventional treatments such as autographs and …

[HTML][HTML] Emerging role of mesenchymal stem/stromal cells (MSCs) and MSCs-derived exosomes in bone-and joint-associated musculoskeletal disorders: a new …

MH Gerami, R Khorram, S Rasoolzadegan… - European Journal of …, 2023 - Springer
Exosomes are membranous vesicles with a 30 to 150 nm diameter secreted by
mesenchymal stem/stromal cells (MSCs) and other cells, such as immune cells and cancer …

[HTML][HTML] Overview of three proliferation pathways (Wnt, Notch, and Hippo) in intestine and immune system and their role in inflammatory bowel diseases (IBDs)

SM Khoramjoo, N Kazemifard… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a disorder, which involves the gastrointestinal (GI) tract
consisting Crohn's disease (CD) and ulcerative colitis (UC). The etiology of this disease is …

[HTML][HTML] Close negative correlation of local and circulating Dickkopf-1 and Sclerostin levels during human fracture healing

J Starlinger, J Santol, G Kaiser, K Sarahrudi - Scientific Reports, 2024 - nature.com
Wnt signaling is critically involved in fracture healing. Existing data predominantly relies on
rodent models. Here, we explored local and circulating Dickkopf-1 (DKK1) levels in patients …

Analysis of Cellular Crosstalk and Molecular Signal between Periosteum-Derived Precursor Cells and Peripheral Cells During Bone Healing Process Using a Paper …

YW Tong, ACY Chen, KF Lei - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Periosteum-derived progenitor cells (PDPCs) are highly promising cell sources that are
indispensable in the bone healing process. Adipose-derived stem cells (ADSCs) are …

[HTML][HTML] Targeting the Wnt signalling pathway in cancer: prospects and perils

HV Shaw, A Koval, VL Katanaev - Swiss medical weekly, 2019 - smw.ch
The Wnt pathway, involved in cancer development and progression, has for a long time
been said to be undruggable, owing to its complexity and involvement in stem cell biology …