Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice
P García-García, R Reyes, D García-Sánchez… - Journal of …, 2022 - Springer
Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The
stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone …
stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone …
In vivo investigation of 3D printed polycaprolactone/graphene electro-active bone scaffolds
Additive manufactured scaffolds are widely used as 3D support structures for tissue
engineering. This paper investigates the mechanisms behind bone regeneration due to the …
engineering. This paper investigates the mechanisms behind bone regeneration due to the …
Crucial role of Lamin A/C in the migration and differentiation of MSCs in bone
Lamin A/C, intermediate filament proteins from the nuclear lamina encoded by the LMNA
gene, play a central role in mediating the mechanosignaling of cytoskeletal forces into …
gene, play a central role in mediating the mechanosignaling of cytoskeletal forces into …
ADSC-based cell therapies for musculoskeletal disorders: a review of recent clinical trials
Recently published clinical trials involving the use of adipose-derived stem cells (ADSCs)
indicated that approximately one-third of the studies were conducted on musculoskeletal …
indicated that approximately one-third of the studies were conducted on musculoskeletal …
[HTML][HTML] Effect of flavonoids from Rhizoma Drynariae on osteoporosis rats and osteocytes
H Jin, N Jiang, W Xu, Z Zhang, Y Yang, J Zhang… - Biomedicine & …, 2022 - Elsevier
In this experimental study, we evaluated the protective effects and the safety of main
flavanones derived from Rhizoma Drynariae (Gusuibu) in vitro and in vivo. The MTT assay …
flavanones derived from Rhizoma Drynariae (Gusuibu) in vitro and in vivo. The MTT assay …
A Review on Pathophysiology, and Molecular Mechanisms of Bacterial Chondronecrosis and Osteomyelitis in Commercial Broilers
VSR Choppa, WK Kim - Biomolecules, 2023 - mdpi.com
Modern day broilers have a great genetic potential to gain heavy bodyweights with a huge
metabolic demand prior to their fully mature ages. Moreover, this made the broilers prone to …
metabolic demand prior to their fully mature ages. Moreover, this made the broilers prone to …
Recent updates on Wnt signaling modulators: a patent review (2014-2020)
VG Goswami, BD Patel - Expert Opinion on Therapeutic Patents, 2021 - Taylor & Francis
Introduction: Wnt signaling is a signal transduction pathway that plays a vital role in
embryonic development and normal tissue preservation. Dysfunction of it gives rise to …
embryonic development and normal tissue preservation. Dysfunction of it gives rise to …
Effect of resveratrol and mesenchymal stem cell monotherapy and combined treatment in management of osteoporosis in ovariectomized rats: role of SIRT1/FOXO3a …
Osteoporosis is a skeletal disorder that is common in postmenopausal women. It is
characterized by deteriorated bone mass and microarchitecture. In this study, we aimed to …
characterized by deteriorated bone mass and microarchitecture. In this study, we aimed to …
[HTML][HTML] Craniofacial sutures: Signaling centres integrating mechanosensation, cell signaling, and cell differentiation
Cranial sutures are dynamic structures in which stem cell biology, bone formation, and
mechanical forces interface, influencing the shape of the skull throughout development and …
mechanical forces interface, influencing the shape of the skull throughout development and …
Genetic profiling of human bone marrow and adipose tissue-derived mesenchymal stem cells reveals differences in osteogenic signaling mediated by graphene
AF MacDonald, RD Trotter, CD Griffin, AJ Bow… - Journal of …, 2021 - Springer
Background In the last decade, graphene surfaces have consistently supported osteoblast
development of stem cells, holding promise as a therapeutic implant for degenerative bone …
development of stem cells, holding promise as a therapeutic implant for degenerative bone …