Growth plates, or physis, are highly specialized cartilage tissues responsible for longitudinal
bone growth in children and adolescents. Chondrocytes that reside in growth plates are …

Osteoporosis is the result of an imbalance in the bone-remodeling process via an increase
in osteoclastic activity and a decrease in osteoblastic activity. Our previous studies have …

Background: The lack of success of standard therapies for medulloblastoma has highlighted
the need to plan a new therapeutic approach. The purpose of this article is to provide an …

Objective. To identify the shared genetic and epigenetic mechanisms between the
osteogenic differentiation of dental pulp stem cells (DPSC) and bone marrow stem cells …

Human pluripotent stem cells can differentiate into any cell type given appropriate signals
and hence have been used to research early human development of many tissues and …

Lithium, the lightest natural-occurring alkali metal with an atomic number of three, stabilizes
the mood to prevent episodes of acute manic and depression. Multiple lines of evidence …

Background and Aims: Recent research has focused on developing nanoparticle and
nanotopography-based technologies for bone regeneration. The Wingless-related …

Aberrant forms of endoplasmic reticulum (ER)-resident chaperones are implicated in loss of
protein quality control in rare diseases. Here we report a novel mutation (p. Asp233Asn) in …

Craniofacial development comprises a complex process in humans in which failures or
disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a …

On the cellular level, osteoporosis (OP) is a result of imbalanced bone remodeling, in which
osteoclastic bone resorption outcompetes osteoblastic bone formation. Currently available …