Extracellular matrix composition and remodeling: Current perspectives on secondary palate formation, cleft lip/palate, and palatal reconstruction
KBS Paiva, CS Maas, PM Santos… - Frontiers in cell and …, 2019 - frontiersin.org
Craniofacial development comprises a complex process in humans in which failures or
disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a …
disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a …
Biased and allosteric modulation of bone cell-expressing G protein-coupled receptors as a novel approach to osteoporosis therapy
A Kalinkovich, G Livshits - Pharmacological Research, 2021 - Elsevier
On the cellular level, osteoporosis (OP) is a result of imbalanced bone remodeling, in which
osteoclastic bone resorption outcompetes osteoblastic bone formation. Currently available …
osteoclastic bone resorption outcompetes osteoblastic bone formation. Currently available …
Mechanotransducive surfaces for enhanced cell osteogenesis, a review
Novel strategies employing mechano-transducing materials eliciting biological outcomes
have recently emerged for controlling cellular behaviour. Targeted cellular responses are …
have recently emerged for controlling cellular behaviour. Targeted cellular responses are …
The role of Wnt/β-catenin pathway mediators in aortic valve stenosis
K Khan, B Yu, C Kiwan, Y Shalal, S Filimon… - Frontiers in cell and …, 2020 - frontiersin.org
Aortic valve stenosis (AVS) is a prevailing and life-threatening cardiovascular disease in
adults over 75 years of age. However, the molecular mechanisms governing the …
adults over 75 years of age. However, the molecular mechanisms governing the …
Mesenchymal stem cell-based therapy for osteoporotic bones: Effects of the interaction between cells from healthy and osteoporotic rats on osteoblast differentiation …
ATP Souza, GP Freitas, HB Lopes, D Weffort… - Life Sciences, 2024 - Elsevier
Aims Cell therapy utilizing mesenchymal stem cells (MSCs) from healthy donors (HE-MSCs)
is a promising strategy for treating osteoporotic bone defects. This study investigated the …
is a promising strategy for treating osteoporotic bone defects. This study investigated the …
[HTML][HTML] PHF1 fusions cause distinct gene expression and chromatin accessibility profiles in ossifying fibromyxoid tumors and mesenchymal cells
J Hofvander, VY Jo, CDM Fletcher, F Puls, U Flucke… - Modern Pathology, 2020 - Elsevier
Ossifying fibromyxoid tumor (OFMT) is a soft tissue tumor frequently displaying gene fusions,
most of which affect the PHF1 gene. PHF1 encodes plant homeodomain finger protein 1 …
most of which affect the PHF1 gene. PHF1 encodes plant homeodomain finger protein 1 …
Knockdown of POSTN inhibits osteogenic differentiation of mesenchymal stem cells from patients with steroid-induced osteonecrosis
L Han, S Gong, R Wang, S Liu, B Wang… - Frontiers in Cell and …, 2020 - frontiersin.org
Steroid-induced osteonecrosis of femoral head (SONFH) is a common and serious
complication caused by long-term and/or excessive use of glucocorticoids (GCs). The …
complication caused by long-term and/or excessive use of glucocorticoids (GCs). The …
Wnt16 elicits a protective effect against fractures and supports bone repair in zebrafish
LM McGowan, E Kague, A Vorster… - Journal of Bone and …, 2021 - academic.oup.com
Bone homeostasis is a dynamic, multicellular process that is required throughout life to
maintain bone integrity, prevent fracture, and respond to skeletal damage. WNT16 has been …
maintain bone integrity, prevent fracture, and respond to skeletal damage. WNT16 has been …
Nanoparticles of naturally occurring PPAR-γ inhibitor betulinic acid ameliorates bone marrow adiposity and pathological bone loss in ovariectomized rats via Wnt/β …
Aims Postmenopausal osteoporosis is one of the world's biggest yet unnoticed health
issues. After ovariectomy, declined estrogen level significantly contributes to the elevation of …
issues. After ovariectomy, declined estrogen level significantly contributes to the elevation of …
[HTML][HTML] The extracellular signal-regulated kinase mitogen-activated protein kinase pathway in osteoblasts
MB Greenblatt, JH Shim, S Bok… - Journal of Bone …, 2022 - ncbi.nlm.nih.gov
Extracellular signal-regulated kinases (ERKs) are evolutionarily ancient signal transducers
of the mitogen-activated protein kinase (MAPK) family that have long been linked to the …
of the mitogen-activated protein kinase (MAPK) family that have long been linked to the …