There are several routes of administration to the brain, including intraparenchymal,
intraventricular, and subarachnoid injections. The blood-brain barrier (BBB) impedes the …

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there
were only 19 biotechology medicines on the market. Currently there are more than 100, with …

Malignant gliomas are one of the deadliest forms of brain cancer and despite advancements
in treatment, patient prognosis remains poor, with an average survival of 15 months …

The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …

Neurodegenerative disorders (NDs) have become a serious health problem worldwide due
to the rapid increase in the number of people that are affected and the constantly aging …

Environmental agents such as pesticides, weedicides and herbicides (collectively referred to
as pesticides) are associated with the onset and pathogenesis of neurodegenerative …

A novel polymeric mixed micelle composed of Pluronic F127 and D-α-tocopheryl
polyethylene glycol succinate (TPGS) was developed to improve the delivery of fluorescent …

Purpose: For the past few decades central nervous system disorders were considered as a
major strike on human health and social system of developing countries. The natural …

Brain metastasis is a fatal disease with limited treatment options and very short survival.
Although systemic chemotherapy has some effect on peripheral metastases of breast …

Inorganic materials, in particular nanoclays and silica nanoparticles, have attracted
enormous attention due to their versatile and tuneable properties, making them ideal …