Chronic diseases are major killers in the modern era. Physical inactivity is a primary cause
of most chronic diseases. The initial third of the article considers: activity and prevention …

The obese are at increased risk for cardiovascular disease and type 2 diabetes. However,
some who are obese have no metabolic abnormalities. So, it is not adipose tissue per se …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

The morbidity and mortality associated with chronic kidney disease (CKD) are primarily
caused by atherosclerosis and cardiovascular disease, which may be in part caused by …

There is an accumulating amount of evidence indicating that lipid oxidation is depressed in
the skeletal muscle of obese individuals. Decrements in fatty acid oxidation (FAO) have …

Obesity is characterized by excessive rates of plasma fatty acid mobilization and uptake,
which play a key role in mediating insulin resistance. While weight loss via diet‐only or a …

The aims of the present study were to characterize the effects of cycling in varying terrain
with the assistance of an electric motor with respect to (1) power output, velocity, and …

Although the increase in fatty acid oxidation after endurance exercise training has been
linked with improvements in insulin sensitivity and overall metabolic health, the mechanisms …

As type 2 diabetes remains a leading cause of morbidity and mortality, identifying the most
appropriate preventive treatment early in the development of disease is an important public …

Obesity-related diseases such as the metabolic syndrome and type 2 diabetes originate, in
part, from the progressive metabolic deterioration of skeletal muscle. A preliminary …