[HTML][HTML] Diversity in chemical structures and biological properties of plant alkaloids
S Bhambhani, KR Kondhare, AP Giri - Molecules, 2021 - mdpi.com
Phytochemicals belonging to the group of alkaloids are signature specialized metabolites
endowed with countless biological activities. Plants are armored with these naturally …
endowed with countless biological activities. Plants are armored with these naturally …
Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors
S Dallavalle, V Dobričić, L Lazzarato, E Gazzano… - Drug Resistance …, 2020 - Elsevier
Multidrug resistance (MDR) is the dominant cause of the failure of cancer chemotherapy.
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that …
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that …
[HTML][HTML] Honey bee products: preclinical and clinical studies of their anti-inflammatory and immunomodulatory properties
HR El-Seedi, N Eid, AA Abd El-Wahed, ME Rateb… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a defense process triggered when the body faces assaults from pathogens,
toxic substances, microbial infections, or when tissue is damaged. Immune and inflammatory …
toxic substances, microbial infections, or when tissue is damaged. Immune and inflammatory …
Natural products: An upcoming therapeutic approach to cancer
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …
anthropogenic factors initiate mutations in different functional genes of growth factors and …
[HTML][HTML] Cancer chemoprevention: A strategic approach using phytochemicals
M Swetha, CK Keerthana, TP Rayginia… - Frontiers in …, 2022 - frontiersin.org
Cancer chemoprevention approaches are aimed at preventing, delaying, or suppressing
tumor incidence using synthetic or natural bioactive agents. Mechanistically …
tumor incidence using synthetic or natural bioactive agents. Mechanistically …
Small molecules regulating reactive oxygen species homeostasis for cancer therapy
J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
Investigation on the effect of fluorescence quenching of calf thymus DNA by piperine: caspase activation in the human breast cancer cell line studies
S Rezaei, HS Meftah, Y Ebtehajpour… - DNA and Cell …, 2024 - liebertpub.com
In this study, we determined the interaction of piperine and calf thymus DNA (ct DNA) in Tris-
HCl buffer solution at pH= 6.8 and also evaluated the binding mechanism through the data …
HCl buffer solution at pH= 6.8 and also evaluated the binding mechanism through the data …
[HTML][HTML] Anticancer applications and pharmacological properties of piperidine and piperine: a comprehensive review on molecular mechanisms and therapeutic …
S Mitra, U Anand, NK Jha, MS Shekhawat… - Frontiers in …, 2022 - frontiersin.org
Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …
ROS‐mediated cancer cell killing through dietary phytochemicals
S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …
[HTML][HTML] Mechanisms of action of fruit and vegetable phytochemicals in colorectal cancer prevention
Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is
expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly …
expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly …