The innate immune system provides the first line of defence against foreign microbes and
particulate materials. Engineered nanoparticles can interact with the immune system in …

Recent years have seen a renaissance in the research linking inflammation and cancer with
immune cells playing a central role in smouldering inflammation in the tumor …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Macrophages (MФs) are the leukocytes produced from differentiation of monocytes and are
located in almost all tissues of human body. They are involved in various processes, such as …

Preclinical characterization of novel nanotechnology-based formulations is often challenged
by physicochemical characteristics, sterility/sterilization issues, safety and efficacy. Such …

In cancer imaging, nanoparticle biodistribution is typically visualized in living subjects using
'bulk'imaging modalities such as magnetic resonance imaging, computerized tomography …

Degenerative diseases are results of deterioration of cells and tissues with aging either by
unhealthy lifestyle or normal senescence. The degenerative disease likely affects central …

The alveolar macrophages defend the lung against airborne pollutants and infectious
microorganisms. Recent advances in the understanding of the role of macrophages in …

The complement system, professional phagocytes and other cells such as Natural killer cells
and mast cells are among the important components of the innate arm of the immune …

Poly (2-methyl-2-oxazoline)(PMOXA) is an alternative promising polymer to poly (ethylene
glycol)(PEG) for design and engineering of macrophage-evading nanoparticles (NPs) …