A comprehensive review and update on the pathogenesis of inflammatory bowel disease
Q Guan - Journal of immunology research, 2019 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic and life‐threating inflammatory disease of
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …
[HTML][HTML] Mechanisms regulating intestinal barrier integrity and its pathological implications
C Chelakkot, J Ghim, SH Ryu - Experimental & molecular medicine, 2018 - nature.com
The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …
cells and the complex environment occur in addition to food digestion. Together with the …
[HTML][HTML] Prevalence of inflammatory bowel disease among adults aged≥ 18 years—United States, 2015
JM Dahlhamer - MMWR. Morbidity and mortality weekly report, 2016 - cdc.gov
Crohn's disease and ulcerative colitis, collectively known as inflammatory bowel disease,
are characterized by chronic inflammation of the gastrointestinal tract. Inflammatory bowel …
are characterized by chronic inflammation of the gastrointestinal tract. Inflammatory bowel …
ROS/RNS and base dual activatable merocyanine‐based NIR‐II fluorescent molecular probe for in vivo biosensing
Inflammation usually results in high‐level reactive oxygen species (ROS) and reactive
nitrogen species (RNS) not only in acidic tissue but also in alkaline tissue. However …
nitrogen species (RNS) not only in acidic tissue but also in alkaline tissue. However …
[HTML][HTML] The CB2 receptor and its role as a regulator of inflammation
C Turcotte, MR Blanchet, M Laviolette… - Cellular and Molecular …, 2016 - Springer
The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …
immune tissues, highlighting the possibility that the endocannabinoid system has an …
[HTML][HTML] Metallothionein 1: A new spotlight on inflammatory diseases
H Dai, L Wang, L Li, Z Huang, L Ye - Frontiers in immunology, 2021 - frontiersin.org
MT1 has been demonstrated to be an essential stress protein in maintaining physiological
balance and regulating immune homeostasis. While the immunological involvement of MT1 …
balance and regulating immune homeostasis. While the immunological involvement of MT1 …
NLRP3: a promising therapeutic target for autoimmune diseases
HH Shen, YX Yang, X Meng, XY Luo, XM Li… - Autoimmunity …, 2018 - Elsevier
NLRP3, a member of nucleotide-binding domain-(NOD) like receptor family, can be found in
large varieties of immune and non-immune cells. Upon activation, the NLRP3, apoptosis …
large varieties of immune and non-immune cells. Upon activation, the NLRP3, apoptosis …
An overview of the mechanism of action of the monoclonal antibody vedolizumab
Vedolizumab is a novel therapeutic monoclonal antibody recently approved for the treatment
of moderately to severely active ulcerative colitis and Crohn's disease in adults who have …
of moderately to severely active ulcerative colitis and Crohn's disease in adults who have …
Impaired intestinal permeability contributes to ongoing bowel symptoms in patients with inflammatory bowel disease and mucosal healing
J Chang, RW Leong, VC Wasinger, M Ip, M Yang… - Gastroenterology, 2017 - Elsevier
Background & Aims Many patients with inflammatory bowel diseases (IBD) have ongoing
bowel symptoms of diarrhea or abdominal pain despite mucosal healing. We investigated …
bowel symptoms of diarrhea or abdominal pain despite mucosal healing. We investigated …
[HTML][HTML] Microbial pathways in colonic sulfur metabolism and links with health and disease
F Carbonero, AC Benefiel… - Frontiers in …, 2012 - frontiersin.org
Sulfur is both crucial to life and a potential threat to health. While colonic sulfur metabolism
mediated by eukaryotic cells is relatively well studied, much less is known about sulfur …
mediated by eukaryotic cells is relatively well studied, much less is known about sulfur …