Background Patients with longstanding ulcerative colitis and colonic Crohn's disease have
an increased risk of colorectal cancer (CRC) compared with the general population. This …

While inflammatory bowel disease (IBD) might be a risk factor in the development of brain
dysfunctions, the underlying mechanisms are largely unknown. Here, mice were treated with …

Advances in synthetic biology now allow for the reprogramming of microorganisms to
execute specific tasks. Here, we describe the development of an engineered strain of E. coli …

Background: Recommendations on breastfeeding under thiopurines are inconsistent due to
limited data. Aim: To assess the risk of infections in offspring breastfed by mothers receiving …

The preference of the sleep/wake cycle can be grouped into categories or chronotypes.
Inflammatory bowel disease (IBD) has been linked to poor sleep quality which correlates …

The preclinical studies in vivo provide means of characterizing physiologic interactions
when our understanding of such processes is insufficient to allow replacement with in vitro …

Epidemiological studies show that both the incidence of inflammatory bowel disease (IBD)
and the proportion of people with obesity and/or obesity-associated metabolic syndrome …

Sažetak Inflammatory bowel disease (IBD) is a heterogeneous group of chronic
inflammatory disorders of the gastrointestinal tract with two main distinguishable entities …

Objectives Drug product performance in patients with gastrointestinal (GI) diseases can be
altered compared to healthy subjects due to pathophysiological changes. In this review …

There are multiple mechanisms that protect the intestine from an excessive inflammatory
response to intestinal microorganisms. We report here that all four mammalian …