Carboxymethyl chitosan microspheres loaded hyaluronic acid/gelatin hydrogels for controlled drug delivery and the treatment of inflammatory bowel disease

S Zhang, L Kang, S Hu, J Hu, Y Fu, Y Hu… - International Journal of …, 2021 - Elsevier
A major drawback of oral treatment of inflammatory bowel disease (IBD) is the non-specific
distribution of drugs during long-term treatment. Despite its effectiveness as an anti …

Oxidative stress and DNA damage: implications in inflammatory bowel disease

C Pereira, D Grácio, JP Teixeira… - Inflammatory bowel …, 2015 - academic.oup.com
This review will focus on published human studies on oxidative stress and DNA damage in
inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease, assessing …

Lineage-specific effects of 1, 25-dihydroxyvitamin D3 on the development of effector CD4 T cells

MT Palmer, YK Lee, CL Maynard, JR Oliver… - Journal of Biological …, 2011 - ASBMB
Vitamin D deficiency is implicated in autoimmune disease. We therefore evaluated the
effects of 1α, 25-dihydroxyvitamin D 3 (1, 25-D 3), the active form of vitamin D, on the …

JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines

S Danese, M Grisham, J Hodge… - American Journal of …, 2016 - journals.physiology.org
The inflammatory diseases ulcerative colitis and Crohn's disease constitute the two main
forms of inflammatory bowel disease (IBD). They are characterized by chronic, relapsing …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

Impact of inflammatory bowel disease on quality of life: Results of the European Federation of Crohn's and Ulcerative Colitis Associations (EFCCA) patient survey

S Ghosh, R Mitchell - Journal of Crohn's and Colitis, 2007 - academic.oup.com
Background: The predominant symptoms of inflammatory bowel disease (IBD) are
diarrhoea, abdominal pain, gastrointestinal bleeding, weight loss, malnutrition and fatigue …

Immune-mediated inflammatory diseases (IMIDs) and biologic therapy: a medical revolution

A Kuek, BL Hazleman, AJK Östör - Postgraduate medical journal, 2007 - academic.oup.com
Targeted biologic therapies have revolutionised treatment of immune-mediated
inflammatory diseases (IMIDs) due to their efficacy, speed of onset and tolerability. The …

A meta-analytic review of the psychosocial adjustment of youth with inflammatory bowel disease

RN Greenley, KA Hommel, J Nebel… - Journal of pediatric …, 2010 - academic.oup.com
Objective To conduct a meta-analytic review of psychosocial adjustment of youth with
inflammatory bowel disease (IBD). Methods Nineteen studies with a total of 1167 youth with …

Tobacco use increases susceptibility to bacterial infection

J Bagaitkar, DR Demuth, DA Scott - Tobacco induced diseases, 2008 - Springer
Active smokers and those exposed to secondhand smoke are at increased risk of bacterial
infection. Tobacco smoke exposure increases susceptibility to respiratory tract infections …

Quantitative Metabolomic Profiling of Serum, Plasma, and Urine by 1H NMR Spectroscopy Discriminates between Patients with Inflammatory Bowel Disease and …

R Schicho, R Shaykhutdinov, J Ngo… - Journal of proteome …, 2012 - ACS Publications
Serologic biomarkers for inflammatory bowel disease (IBD) have yielded variable
differentiating ability. Quantitative analysis of a large number of metabolites is a promising …