Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice

R Ito, M Shin-Ya, T Kishida, A Urano… - Clinical & …, 2006 - academic.oup.com
Cytokines may be crucially involved in the pathogenesis of inflammatory bowel diseases
(IBD), but it remains controversial whether interferon (IFN)-γ, a typical proinflammatory …

Ulcerative colitis and perfluorooctanoic acid (PFOA) in a highly exposed population of community residents and workers in the mid-Ohio valley

K Steenland, L Zhao, A Winquist… - Environmental health …, 2013 - ehp.niehs.nih.gov
Background: Little is known about environmental determinants of autoimmune diseases.
Objectives: We studied autoimmune diseases in relation to level of exposure to …

Wielding the double-edged sword: Redox drug delivery systems for inflammatory bowel disease

Y Chen, M Shui, Q Yuan, CT Vong, Z Yang… - Journal of Controlled …, 2023 - Elsevier
The etiology of inflammatory bowel disease (IBD) is extremely complex and related to an
excessive immune response that results in the pathologically release of reactive oxygen …

Omega-3 fatty acid-derived mediators 17 (R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice

AF Bento, RF Claudino, RC Dutra… - The Journal of …, 2011 - journals.aai.org
Resolvins of the D series are generated from docosahexaenoic acid, which are enriched in
fish oils and are believed to exert beneficial roles on diverse inflammatory disorders …

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection

T Gobbetti, J Dalli, RA Colas… - Proceedings of the …, 2017 - National Acad Sciences
The resolution of inflammation is an active process orchestrated by specialized proresolving
lipid mediators (SPM) that limit the host response within the affected tissue; failure of …

[HTML][HTML] Evaluating the oxidative stress in inflammation: role of melatonin

A Sánchez, AC Calpena, B Clares - International journal of molecular …, 2015 - mdpi.com
Oxygen is used by eukaryotic cells for metabolic transformations and energy production in
mitochondria. Under physiological conditions, there is a constant endogenous production of …

Interactions between diet, bile acid metabolism, gut microbiota, and inflammatory bowel diseases

S Devkota, EB Chang - Digestive diseases, 2015 - karger.com
The composite human gut microbiomes of Western populations have changed over the past
century, brought on by new environmental triggers that often have a negative impact on …

Role of toll-like receptors in inflammatory bowel disease

N Kordjazy, A Haj-Mirzaian, A Haj-Mirzaian… - Pharmacological …, 2018 - Elsevier
Inflammatory bowel disease (IBD) is the chronic inflammation of the gastrointestinal tract.
Recently, studies of the interplay between the adaptive and innate immune responses have …

[HTML][HTML] Therapeutic Potential of Bioactive Components from Scutellaria baicalensis Georgi in Inflammatory Bowel Disease and Colorectal Cancer: A Review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2023 - mdpi.com
Scutellaria baicalensis Georgi (SBG), an herbal medicine with various biological activities,
including anti-inflammatory, anticancer, antiviral, antibacterial, and antioxidant activities, is …

[HTML][HTML] Incidence and prevalence rates of inflammatory bowel diseases, in midwestern of São Paulo State, Brazil

CR Victoria, LY Sassak, HRC Nunes - Arquivos de gastroenterologia, 2009 - SciELO Brasil
CONTEXT: The incidence and populational prevalence of inflammatory bowel diseases,
hitherto unknown in Brazil, were estimated for a region in the Midwest of São Paulo State …