Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease

M Craven, CE Egan, SE Dowd, SP McDonough… - PloS one, 2012 - journals.plos.org
Background and Aims Understanding the interplay between genetic susceptibility, the
microbiome, the environment and the immune system in Crohn's Disease (CD) is essential …

Antioxidant activity of an exopolysaccharide purified from Lactococcus lactis subsp. lactis 12

D Pan, X Mei - Carbohydrate polymers, 2010 - Elsevier
A novel exopolysaccharide (EPS) was obtained by ultra-filtration, ion exchange and sizing
chromatography from a culture of Lactococcus lactis subsp. lactis 12. The EPS was mainly …

Maggot extracts alleviate inflammation and oxidative stress in acute experimental colitis via the activation of Nrf2

R Wang, Y Luo, Y Lu, D Wang, T Wang… - Oxidative Medicine …, 2019 - Wiley Online Library
Ulcerative colitis (UC) is a common chronic remitting disease driven through altered immune
responses with production of inflammatory cytokines. Oxidant/antioxidant balance is also …

The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23→ IL-17 axis

AF Sheibanie, JH Yen, T Khayrullina… - The Journal of …, 2007 - journals.aai.org
Although Crohn's disease has been traditionally considered to be Th1-mediated, the newly
identified Th17 cells emerged recently as crucial participants. Th1/Th17 differentiation is …

Oxidative stress in ulcerative colitis-associated carcinogenesis

A Roessner, D Kuester, P Malfertheiner… - … -Research and practice, 2008 - Elsevier
Oxidative stress is defined as an imbalance between generation of reactive oxygen species
(ROS) and decreased antioxidant defense systems. Oxidative stress develops particularly in …

Environmental factors in inflammatory bowel disease: a case-control study based on a Danish inception cohort

TS Hansen, T Jess, I Vind, M Elkjaer… - Journal of Crohn's …, 2011 - academic.oup.com
Background: The role of environmental factors in development of inflammatory bowel
disease (IBD) remains uncertain. The aim of the present study was to assess a number of …

ImproveCareNow: the development of a pediatric inflammatory bowel disease improvement network

W Crandall, MD Kappelman, RB Colletti… - Inflammatory bowel …, 2011 - academic.oup.com
There is significant variation in diagnostic testing and treatment for inflammatory bowel
disease. Quality improvement science methods can help address unwarranted variations in …

Chronic inflammatory diseases and cardiovascular risk: a systematic review

I Roifman, PL Beck, TJ Anderson, MJ Eisenberg… - Canadian Journal of …, 2011 - Elsevier
Despite recent advancements in the treatment of coronary artery disease (CAD), it remains
the number one cause of death in the world. While traditional risk factors partially account for …

Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease

S Sepehri, R Kotlowski, CN Bernstein… - Inflammatory bowel …, 2007 - academic.oup.com
Background Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition without
any known cause or cure. An imbalance in normal gut biota has been identified as an …

Inflammatory bowel disease and risk of ischemic heart disease: an updated meta‐analysis of cohort studies

W Feng, G Chen, D Cai, S Zhao, J Cheng… - Journal of the American …, 2017 - Am Heart Assoc
Background Several immune‐mediated diseases have been shown to be associated with
an increased risk of cardiovascular disease. However, studies evaluating the association …