Inflammatory bowel disease: current insights into pathogenesis and new therapeutic options; probiotics, prebiotics and synbiotics

MS Geier, RN Butler, GS Howarth - International journal of food …, 2007 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing disorder involving a dysregulated
host–microbiota interaction. IBD patients have been shown to possess an increased risk for …

Inflammatory bowel disease and risk of ischemic heart disease: an updated meta‐analysis of cohort studies

W Feng, G Chen, D Cai, S Zhao, J Cheng… - Journal of the American …, 2017 - Am Heart Assoc
Background Several immune‐mediated diseases have been shown to be associated with
an increased risk of cardiovascular disease. However, studies evaluating the association …

Anti‐inflammatory effects of phytosteryl ferulates in colitis induced by dextran sulphate sodium in mice

MS Islam, T Murata, M Fujisawa… - British journal of …, 2008 - Wiley Online Library
Background and purpose: We have recently reported that phytosteryl ferulates isolated from
rice bran inhibit nuclear factor‐κB (NF‐κB) activity in macrophages. In the present study, we …

Inflammatory bowel disease: exploring gut pathophysiology for novel therapeutic targets

V Yadav, F Varum, R Bravo, E Furrer, D Bojic… - Translational …, 2016 - Elsevier
Ulcerative colitis and Crohn's disease are the 2 major phenotypes of inflammatory bowel
disease (IBD), which are influenced by a complex interplay of immunological and genetic …

Faecal S100A12 as a non-invasive marker distinguishing inflammatory bowel disease from irritable bowel syndrome

T Kaiser, J Langhorst, H Wittkowski, K Becker… - Gut, 2007 - gut.bmj.com
Objective: S100A12 is a pro-inflammatory protein that is secreted by granulocytes. S100A12
serum levels increase during inflammatory bowel disease (IBD). We performed the first study …

Nuclear receptors versus inflammation: mechanisms of transrepression

G Pascual, CK Glass - Trends in Endocrinology & Metabolism, 2006 - cell.com
Inflammation is a beneficial host response to external challenge or cellular injury that leads
to the activation of a complex array of inflammatory mediators, finalizing the restoration of …

The relationship of mucosal bacteria to duodenal histopathology, cytokine mRNA, and clinical disease activity in cats with inflammatory bowel disease

S Janeczko, D Atwater, E Bogel, A Greiter-Wilke… - Veterinary …, 2008 - Elsevier
Feline inflammatory bowel disease (IBD) is the term applied to a group of poorly understood
enteropathies that are considered a consequence of uncontrolled intestinal inflammation in …

Astragalus membranaceus Extract Attenuates Inflammation and Oxidative Stress in Intestinal Epithelial Cells via NF-κB Activation and Nrf2 Response

S Adesso, R Russo, A Quaroni, G Autore… - International Journal of …, 2018 - mdpi.com
Astragalus membranaceus, dried root extract, also known as Astragali radix, is used in
traditional Chinese medicine as a tonic remedy. Moreover, it has been reported that …

The role of polymorphonuclear leukocyte trafficking in the perpetuation of inflammation during inflammatory bowel disease

JC Brazil, NA Louis, CA Parkos - Inflammatory bowel diseases, 2013 - academic.oup.com
The inflammatory bowel diseases (IBDs; Crohn's disease, and ulcerative colitis) are
chronically relapsing inflammatory disorders of the intestine and/or colon. The precise …

Mechanisms of microbial hydrogen disposal in the human colon and implications for health and disease

N Nakamura, HC Lin, CS McSweeney… - Annual review of …, 2010 - annualreviews.org
In the human gastrointestinal tract, dietary components, including fiber, that reach the colon
are fermented principally to short-chain fatty acids, hydrogen, and carbon dioxide. Microbial …