Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice

K Shang, YP Bai, C Wang, Z Wang, HY Gu, X Du… - PloS one, 2012 - journals.plos.org
Ulcerative colitis (UC) is a major form of chronic inflammation that can frequently progress to
colon cancer. Several studies have demonstrated massive infiltration of neutrophils and …

Isotretinoin use and the risk of inflammatory bowel disease: a case–control study

SD Crockett, CQ Porter, CF Martin… - Official journal of the …, 2010 - journals.lww.com
OBJECTIVES: Isotretinoin is commonly prescribed for the treatment of severe acne.
Although cases of inflammatory bowel disease (IBD) have been reported in isotretinoin …

Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases

H Ali, B Weigmann, MF Neurath, EM Collnot… - Journal of Controlled …, 2014 - Elsevier
The purpose of this study was to investigate the therapeutic potential of budesonide loaded
nanocarriers for the treatment of inflammatory bowel disease (IBD). First, budesonide was …

Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in …

L Frolova, P Drastich, P Rossmann… - … of Histochemistry & …, 2008 - journals.sagepub.com
Dysregulation of innate and adaptive intestinal immune responses to bacterial microbiota is
supposed to be involved in pathogenetic mechanisms of inflammatory bowel diseases …

Clinical characteristics of inflammatory bowel disease in Turkey: a multicenter epidemiologic survey

N Tozun, O Atug, N Imeryuz… - Journal of clinical …, 2009 - journals.lww.com
Aim To investigate the epidemiologic and clinical characteristics of inflammatory bowel
disease (IBD) patients in a large multicenter, countrywide, hospital-based study in Turkey …

The safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn's disease–a phase 1 trial with three doses

T Dhere, I Copland, M Garcia… - Alimentary …, 2016 - Wiley Online Library
Background Mesenchymal stromal cells ability to reset immune functionalities may be useful
in Crohn's disease. Aim To perform a first‐in‐human phase 1 safety clinical trial of …

Retinoic acid, leaky gut, and autoimmune diseases

L Abdelhamid, XM Luo - Nutrients, 2018 - mdpi.com
A leaky gut has been observed in a number of autoimmune diseases including type 1
diabetes, multiple sclerosis, inflammatory bowel disease, and systemic lupus …

Inflammatory bowel disease-specific health-related quality of life instruments: a systematic review of measurement properties

XL Chen, L Zhong, Y Wen, TW Liu, XY Li… - Health and quality of life …, 2017 - Springer
Background This review aims to critically appraise and compare the measurement
properties of inflammatory bowel disease (IBD)-specific health-related quality of life …

Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium–induced colitis

T Ishida, M Yoshida, M Arita, Y Nishitani… - Inflammatory bowel …, 2010 - academic.oup.com
Background Resolvin E1 (RvE1), an endogenous lipid mediator derived from
eicosapentaenoic acid, has been identified in local inflammation during the healing stage …

Scheduled infliximab monotherapy to prevent recurrence of Crohn's disease following ileocolic or ileal resection: a 3-year prospective randomized open trial

K Yoshida, K Fukunaga, H Ikeuchi… - Inflammatory bowel …, 2012 - academic.oup.com
Background Infliximab (IFX) is effective for remission induction and maintenance of Crohn's
disease (CD). This trial assessed the efficacy of scheduled maintenance IFX monotherapy to …